Microtubules are highly dynamic polymers of α/β tubulin heterodimers that play key roles in
cell division and in organizing cell cytoplasm. Although they have been discovered more …

Microtubules have important functions ranging from maintenance of cell morphology to
subcellular transport, cellular signaling, cell migration, and formation of cell polarity. At the …

Simple Summary Microtubules (MTs) are dynamic structures that compose part of the cell
cytoskeleton. They play important roles in various cellular functions, such as intracellular …

Acetylation is a well-studied post-translational modification (PTM) of tubulin. Acetylated
tubulin is present in the centrioles, primary cilia, and flagella, which contain long-lived stable …

Tubulin posttranslational modifications are currently emerging as important regulators of the
microtubule cytoskeleton and thus have a strong potential to be implicated in a number of …

Among the different types of cytoskeletal components, microtubules arguably accumulate
the greatest diversity of post-translational modifications (PTMs). Acetylation of lysine 40 …

Tubulin is subject to a post-translational acetylation reaction that is thought to be correlated
with increased stability of the modified microtubules (MTs). We sought to test directly the …

Tubulin undergoes posttranslational modifications proposed to specify microtubule
subpopulations for particular functions. Most of these modifications occur on the C-termini of …

Microtubules (MTs) are an essential component of the neuronal cytoskeleton; they are
involved in various aspects of neuron development, maintenance, and functions including …

Across different cell types and tissues, microtubules are assembled from highly conserved
dimers of α‐and β‐tubulin. Despite their highly similar structures, microtubules have …