Expression of long noncoding RNAs in the ovarian granulosa cells of women with diminished ovarian reserve using high-throughput sequencing

L Dong, X Xin, HM Chang, PCK Leung, C Yu… - Journal of Ovarian …, 2022 - Springer
Background Infertility is a global reproductive-health problem, and diminished ovarian
reserve (DOR) is one of the common causes of female infertility. Long noncoding RNAs …

Role of lncRNAs in the pathogenic mechanism of human decreased ovarian reserve

Z Lv, Z Lv, L Song, Q Zhang, S Zhu - Frontiers in Genetics, 2023 - frontiersin.org
Decreased ovarian reserve (DOR) is defined as a decrease in the quality and quantity of
oocytes, which reduces ovarian endocrine function and female fertility. The impaired …

High-throughput sequencing profiles about lncRNAs and mRNAs of ovarian granulosa cells in polycystic ovary syndrome

Y Zheng, Y Bian, R Wu, W Chen, L Fu, P Li… - Frontiers in …, 2021 - frontiersin.org
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in
women of reproductive age, which is characterized by ovulatory dysfunction, clinical and/or …

Long non-coding RNAs in ovarian granulosa cells

J Tu, Y Chen, Z Li, H Yang, H Chen, Z Yu - Journal of Ovarian Research, 2020 - Springer
Granulosa cells (GCs) are somatic cells surrounding oocytes within follicles and are
essential for folliculogenesis. Pathological changes in GCs are found in several ovarian …

Profiles for long non-coding RNAs in ovarian granulosa cells from women with PCOS with or without hyperandrogenism

L Jin, Q Yang, C Zhou, L Liu, H Wang, M Hou… - Reproductive …, 2018 - Elsevier
Research question What is the expression pattern of long non-coding RNAs (lncRNA) in
ovarian granulosa cells of women with polycystic ovary syndrome (PCOS) with or without …

Comprehensive analysis of lncRNA-miRNA-mRNA ceRNA network and key genes in granulosa cells of patients with biochemical primary ovarian insufficiency

B Liu, L Liu, Z Sulaiman, C Wang, L Wang… - Journal of Assisted …, 2024 - Springer
Primary ovarian insufficiency (POI) is a common condition leading to the pathological
decline of ovarian function in women of reproductive age, resulting in amenorrhea …

Transcriptional profiling of long noncoding RNAs and their target transcripts in ovarian cortical tissues from women with normal menstrual cycles and primary ovarian …

G Yao, J He, Y Kong, J Zhai, Y Xu… - Molecular …, 2019 - Wiley Online Library
Previous studies have shown that long noncoding RNAs (lncRNAs) show a highly tissue‐
and disease‐specific expression pattern and that they regulate the expression of …

Long noncoding RNAs: potential regulators involved in the pathogenesis of polycystic ovary syndrome

Y Liu, Y Li, S Feng, D Ye, X Chen, X Zhou… - Endocrinology, 2017 - academic.oup.com
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility in
women of reproductive age, and its etiology remains poorly understood. Altered activities of …

Construction of a ceRNA-based lncRNA–mRNA network to identify functional lncRNAs in premature ovarian insufficiency

C Luo, J Zhang, L Bo, L Wei, G Yang, S Gao… - Frontiers in …, 2022 - frontiersin.org
Premature ovarian insufficiency, characterized by ovarian infertility and low fertility, has
become a significant problem in developed countries due to its propensity for late delivery. It …

Down-regulation of long non-coding RNAs in reproductive aging and analysis of the lncRNA-miRNA-mRNA networks in human cumulus cells

A Caponnetto, R Battaglia, C Ferrara, ME Vento… - Journal of Assisted …, 2022 - Springer
Abstract Purpose Long non-coding RNAs (lncRNAs) control gene expression at multiple
levels. By interacting with microRNAs (miRNAs), they regulate their mRNA targets creating …