Timely and accurate detection of the causal agent of a disease is crucial to restrict suffering
and save lives. Mere symptoms are often not enough to detect the root cause of the disease …

Nucleic acid sequence-based amplification (NASBA) is a sensitive and efficient molecular
tool for amplification of RNA and has been widely adopted in clinical diagnostics. Monitoring …

Many infectious diseases that affect global health are most accurately diagnosed through
nucleic acid amplification and detection. However, existing nucleic acid amplification tests …

BACKGROUND 0001. The technology of repeatedly amplifying nucleic acids in a sample,
the polymerase chain reaction (PCR), has greatly broadened our capabilities of studying …

The ongoing pandemic and increasing frequency of infectious disease outbreaks due to
climate change, urbanization, and global human migration have put great focus on nucleic …

Nucleic acid amplification testing facilitates the detection of disease through specific
genomic sequences and is attractive for point-of-need testing (PONT); in particular, the early …

The recurring instances of infectious disease outbreaks, coupled with complications such as
comorbidity challenges and antibiotic resistance, consistently underscore the limitations …

Nucleic Acid Testing for Human Disease describes various techniques including target and
signal amplification-based NAT procedures, microarrays, bead-based multiplex assays, in …

Techniques using nucleic acid amplification have not had the same amount of impact on
research and clinical diagnosis in the developing world as that observed in the West. This is …

The tremendous increase in DNA sequencing capacity arising from the commercialization of
“next generation” instruments has opened the door to innumerable routes of investigation in …