Several strains that grow on medium-chain-length alkanes and catalyze interesting
hydroxylation and epoxidation reactions do not possess integral membrane nonheme iron …

The first and key step in alkane metabolism is the terminal hydroxylation of alkanes to 1-
alkanols, a reaction catalyzed by a family of integral-membrane diiron enzymes related to …

Enzymes of the AlkB and CYP153 families catalyze the first step in the catabolism of medium-
chain-length alkanes, selective oxidation of the alkane to the 1-alkanol, and enable their …

Alkane hydroxylases, including the integral‐membrane non‐haem iron monooxygenase
(AlkB) and cytochrome P450 CYP153 family, are key enzymes in bacterial alkane oxidation …

We have studied the hydroxylation of a wide range of linear, branched, and cyclic alkanes
and alkylbenzenes by the alkane hydroxylase system of Pseudomonas oleovorans GPo1 in …

The cytochrome P450 CYP153 family is thought to mediate the terminal hydroxylation
reactions of n-alkanes. We isolated 16 new P450 CYP153A genes (central region) from …

CYP153 a cytochrome P450 from Acinetobacter sp. EB104 catalyzes the hydroxylation of
unsubstituted n-alkanes. We have decided to use the CYP153 system as a model for …

Cytochrome P450 monooxygenases (P450s) are known to oxidize hydrocarbons, albeit with
limited substrate specificity across classes of these compounds. Here we report a P450 …

The first step in the aerobic degradation of alkanes by bacteria, yeasts, and fungi is
catalyzed by oxygenases. These enzymes, which introduce oxygen atoms derived from …

The oxofunctionalization of saturated hydrocarbons is an important goal in basic and
applied chemistry. Biocatalysts like cytochrome P450 enzymes can introduce oxygen into a …