Breast cancer is a challenging health issue in women and the second-leading cause of
mortality around world. In this review, we addressed beneficial role of siRNA to control …

Recently, nucleic acid drugs have been considered as promising candidates in treatment of
various diseases, especially cancer. Because of developing resistance to conventional …

Triple negative breast cancer (TNBC) is one of the most aggressive types of breast cancer.
Owing to the absenteeism of hormonal receptors expressed at the cancerous breast cells …

Utilizing small interfering RNA (siRNA) as a treatment for cancer, a disease largely driven by
genetic aberrations, shows great promise. However, implementing siRNA therapy in clinical …

RNAi is a remarkable treatment strategy to knock down gene overexpression in a variety of
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …

Globally, breast cancer is the second leading cause of cancer-related mortality among
women, with approximately 1.4 million new cases diagnosed annually. Associated genetic …

Overexpression of oncogenes and cross-talks of the oncoproteins-regulated signaling
cascades with other intracellular pathways in breast cancer could lead to massive abnormal …

Small interfering RNA (siRNA) has an established and precise mode of action to achieve
protein knockdown. With the ability to target any protein, it is very attractive as a potential …

Finding out predisposition and makeup alterations in cancer cells has prompted the
exploration of exogenous small interference RNA (siRNA) as a therapeutic agent to deal …

Nanobiopolymers such as chitosan, gelatin, hyaluronic acid, polyglutamic acid, lipids,
peptides, exosomes, etc., delivery systems have prospects to help overwhelmed …