[HTML][HTML] Neuroglobin is an endogenous neuroprotectant for retinal ganglion cells against glaucomatous damage

X Wei, Z Yu, KS Cho, H Chen, MTA Malik… - The American journal of …, 2011 - Elsevier
Neuroglobin (NGB), a newly discovered member of the globin superfamily, may regulate
neuronal survival under hypoxia or oxidative stress. Although NGB is greatly expressed in …

A possible role of neuroglobin in the retina after optic nerve injury: a comparative study of zebrafish and mouse retina

K Sugitani, Y Koriyama, K Ogai, K Wakasugi… - Retinal Degenerative …, 2016 - Springer
Neuroglobin (Ngb) is a new member of the family of heme proteins and is specifically
expressed in neurons of the central and peripheral nervous systems in all vertebrates. In …

Neuroglobin in retinal neurodegeneration: A potential target in therapeutic approaches

V Solar Fernandez, M Marino, M Fiocchetti - Cells, 2021 - mdpi.com
Retinal neurodegeneration affects an increasing number of people worldwide causing
vision impairments and blindness, reducing quality of life, and generating a great economic …

A novel function of neuroglobin for neuroregeneration in mice after optic nerve injury

K Sugitani, Y Koriyama, M Sera, K Arai, K Ogai… - Biochemical and …, 2017 - Elsevier
Neuroglobin (Ngb) is a recently discovered heme protein in the vertebrate brain that can
bind to oxygen molecules. Mammalian Ngb plays a crucial role in neuroprotection under …

Neuroglobin can prevent or reverse glaucomatous progression in DBA/2J mice

H Cwerman-Thibault, C Lechauve, S Augustin… - … therapy Methods & …, 2017 - cell.com
Mitochondrial dysfunction is responsible for hereditary optic neuropathies. We wished to
determine whether preserving mitochondrial bioenergetics could prevent optic neuropathy …

[HTML][HTML] Neuroglobin involvement in respiratory chain function and retinal ganglion cell integrity

C Lechauve, S Augustin, H Cwerman-Thibault… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Neuroglobin is a member of the globin superfamily expressed in vertebrate brain and retina.
The protein is thought to be involved in neuronal protection from hypoxia or oxidative stress …

Neuroglobin in normal retina and retina from eyes with advanced glaucoma

R Rajendram, NA Rao - British journal of ophthalmology, 2007 - bjo.bmj.com
Background: Neuroglobin is a neurone specific respiratory protein that reversibly binds
oxygen. Neuroglobin was discovered in 2000, initially in brain and later, at a 100 times …

Effects of Exogenous Neuroglobin (Ngb) on retinal inflammatory chemokines and microglia in a rat model of transient hypoxia

SBB Tun, VA Barathi, CD Luu, MN Lynn, ASY Chan - Scientific Reports, 2019 - nature.com
Neuroglobin is an endogenous neuroprotective protein. We determined the safety of direct
delivery of Neuroglobin in the rat retina and its effects on retinal inflammatory chemokines …

Neuroglobin involvement in visual pathways through the optic nerve

C Lechauve, S Augustin, D Roussel, JA Sahel… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Neuroglobin is a member of the globin superfamily proposed to be only expressed in
neurons and involved in neuronal protection from hypoxia or oxidative stress. A significant …

Neuroglobin gene therapy prevents optic atrophy and preserves durably visual function in Harlequin mice

C Lechauve, S Augustin, H Cwerman-Thibault… - Molecular Therapy, 2014 - cell.com
Neuroglobin (NGB) is considered as an endogenous neuroprotective molecule against
stroke, since the protein alleviates the adverse effects of hypoxic and ischemic insults. We …