Glutamate is an inhibitory neurotransmitter in the Drosophila olfactory system

WW Liu, RI Wilson - … of the National Academy of Sciences, 2013 - National Acad Sciences
Glutamatergic neurons are abundant in the Drosophila central nervous system, but their
physiological effects are largely unknown. In this study, we investigated the effects of …

Role of GABAergic inhibition in shaping odor-evoked spatiotemporal patterns in the Drosophila antennal lobe

RI Wilson, G Laurent - Journal of Neuroscience, 2005 - Soc Neuroscience
Drosophila olfactory receptor neurons project to the antennal lobe, the insect analog of the
mammalian olfactory bulb. GABAergic synaptic inhibition is thought to play a critical role in …

[HTML][HTML] Electrical coupling between olfactory glomeruli

E Yaksi, RI Wilson - Neuron, 2010 - cell.com
In the Drosophila antennal lobe, excitation can spread between glomerular processing
channels. In this study, we investigated the mechanism of lateral excitation. Dual recordings …

Mechanisms underlying olfactory neuronal connectivity in Drosophila—the atonal lineage organizes the periphery while sensory neurons and glia pattern the olfactory …

D Jhaveri, A Sen, V Rodrigues - Developmental biology, 2000 - Elsevier
Patterning of the antennal lobe of adult Drosophila occurs through a complex interaction
between sensory neurons, glia, and central neurons of larval and adult origin. Neurons from …

Simultaneous encoding of odors by channels with diverse sensitivity to inhibition

EJ Hong, RI Wilson - Neuron, 2015 - cell.com
Odorant receptors in the periphery map precisely onto olfactory glomeruli (" coding
channels") in the brain. However, the odor tuning of a glomerulus is not strongly correlated …

[HTML][HTML] Excitatory interactions between olfactory processing channels in the Drosophila antennal lobe

SR Olsen, V Bhandawat, RI Wilson - Neuron, 2007 - cell.com
Each odorant receptor gene defines a unique type of olfactory receptor neuron (ORN) and a
corresponding type of second-order neuron. Because each odor can activate multiple ORN …

GABAergic projection neurons route selective olfactory inputs to specific higher-order neurons

L Liang, Y Li, CJ Potter, O Yizhar, K Deisseroth… - Neuron, 2013 - cell.com
We characterize an inhibitory circuit motif in the Drosophila olfactory system, parallel
inhibition, which differs from feedforward or feedback inhibition. Excitatory and GABAergic …

Processing of odor mixtures in the Drosophila antennal lobe reveals both global inhibition and glomerulus-specific interactions

AF Silbering, CG Galizia - Journal of Neuroscience, 2007 - Soc Neuroscience
To understand how odor information is represented and processed in the antennal lobe (AL)
of Drosophila melanogaster, we have optically recorded glomerular calcium responses to …

Variant ionotropic glutamate receptors as chemosensory receptors in Drosophila

R Benton, KS Vannice, C Gomez-Diaz, LB Vosshall - Cell, 2009 - cell.com
Ionotropic glutamate receptors (iGluRs) mediate neuronal communication at synapses
throughout vertebrate and invertebrate nervous systems. We have characterized a family of …

[HTML][HTML] Blockade of neurotransmission in Drosophila mushroom bodies impairs odor attraction, but not repulsion

Y Wang, AS Chiang, S Xia, T Kitamoto, T Tully… - Current Biology, 2003 - cell.com
Olfaction can elicit a rich perceptual experience. It is not known, however, whether olfactory
information is decomposed into various components and processed in distinct perceptual …