[HTML][HTML] Gene set enrichment analysis indicates convergence in the mTOR signalling pathway between syndromic and non-syndromic autism
Autism is a developmental disorder that affects around 62.1 million people globally.
Estimates of its prevalence have been on the rise. Recent research suggests that in the …
Estimates of its prevalence have been on the rise. Recent research suggests that in the …
Network-based integrative analysis of genomics, epigenomics and transcriptomics in autism spectrum disorders
N Di Nanni, M Bersanelli, FA Cupaioli… - International journal of …, 2019 - mdpi.com
Current studies suggest that autism spectrum disorders (ASDs) may be caused by many
genetic factors. In fact, collectively considering multiple studies aimed at characterizing the …
genetic factors. In fact, collectively considering multiple studies aimed at characterizing the …
Disruption of mTOR and MAPK pathways correlates with severity in idiopathic autism
R Eleonora, B Battan, S Martina, F Hollis… - Translational …, 2019 - search.proquest.com
The molecular signature underlying autism spectrum disorder remains largely unknown.
This study identifies differential expression of mTOR and MAPK pathways in patients …
This study identifies differential expression of mTOR and MAPK pathways in patients …
Disruption of mTOR and MAPK pathways correlates with severity in idiopathic autism
E Rosina, B Battan, M Siracusano, L Di Criscio… - Translational …, 2019 - nature.com
The molecular signature underlying autism spectrum disorder remains largely unknown.
This study identifies differential expression of mTOR and MAPK pathways in patients …
This study identifies differential expression of mTOR and MAPK pathways in patients …
Meta-analysis of whole-transcriptome data for prediction of novel genes associated with autism spectrum disorder
DH Le, NT Van - Proceedings of the 8th International Conference on …, 2017 - dl.acm.org
Autism spectrum disorder (ASD) is a common heterogeneous neurodevelopmental disorder
with typical symptoms such as impaired social interaction, language and communication …
with typical symptoms such as impaired social interaction, language and communication …
Meta‐analysis of gene expression in autism spectrum disorder
Autism spectrum disorders (ASD) are clinically heterogeneous and biologically complex. In
general it remains unclear, what biological factors lead to changes in the brains of autistic …
general it remains unclear, what biological factors lead to changes in the brains of autistic …
Integrated Analysis and Identification of Genetic Risk Alleles Related to Autism Spectrum Disorder
Y Wu, P Wang - 2023 11th International Conference on …, 2023 - ieeexplore.ieee.org
Autism spectrum disorder (ASD) is a range of conditions, including difficulties in cognition,
social interaction, communication, and repetitive motion. To understand the mechanism of …
social interaction, communication, and repetitive motion. To understand the mechanism of …
Unveiling promising drug targets for autism spectrum disorder: insights from genetics, transcriptomics, and proteomics
R Jiang, W Huang, X Qiu, J Chen, R Luo… - Briefings in …, 2024 - academic.oup.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder for which
current treatments are limited and drug development costs are prohibitive. Identifying drug …
current treatments are limited and drug development costs are prohibitive. Identifying drug …
Dysfunctional mTORC1 signaling: a convergent mechanism between syndromic and nonsyndromic forms of autism spectrum disorder?
J Magdalon, SM Sánchez-Sánchez… - International Journal of …, 2017 - mdpi.com
Whereas autism spectrum disorder (ASD) exhibits striking heterogeneity in genetics and
clinical presentation, dysfunction of mechanistic target of rapamycin complex 1 (mTORC1) …
clinical presentation, dysfunction of mechanistic target of rapamycin complex 1 (mTORC1) …
Abnormal mTOR Signaling Pathway Activity in Autism Spectrum Disorders: Prospects of Mechanism-Based Therapy
EA Trifonova, AA Kotliarova, AV Kochetov - Molecular Biology, 2023 - Springer
Autism spectrum disorder (ASD) is a developmental disorder characterized by the early
onset of problems with communication, learning, and behavior. The syndromic form of ASD …
onset of problems with communication, learning, and behavior. The syndromic form of ASD …