Lactose is the most commonly used excipient in carrier-based dry powder inhalation (DPI)
formulations. Numerous inhalation therapies have been developed using lactose as a …

Highlights•Applications of alternative carriers to lactose in DPIs are reviewed.•Lactose, the
most commonly used carrier in DPI formulations, has some limitations.•These limitations …

Dry powder inhaler (DPI) products have traditionally comprised a simple formulation of
micronised drug mixed with a carrier excipient, typically lactose monohydrate. The presence …

A dry powder inhaler (DPI) is a dosage form that consists of a powder formulation in a device
which is designed to deliver an active ingredient to the respiratory tract. It has been …

Dry powder inhaler (DPI) is generally formulated as a powder mixture of coarse carrier
particles and micronized drug with aerodynamic diameters of 1-5 μm. Carrier particles are …

Many years of research have not led to a profound knowledge of the mechanisms involved
in the formulation and dispersion of carrier based mixtures for inhalation. Although it is well …

Medicines for delivering therapeutic agents to the lung as dry powders primarily consist of a
carrier and a micronised active pharmaceutical ingredient (API). The performance of an …

The purpose of this study was to evaluate the relationships between physicochemical
properties and aerosolisation performance of different grades of lactose. In order to get a …

This study aims to investigate the effect of carrier characteristics and dosator capsule filling
operation on the in vitro deposition of mixtures containing salbutamol sulphate (SS) and …

The delivery efficiency of dry-powder products for inhalation is dependent upon the drug
formulation, the inhaler device, and the inhalation technique. Dry powder formulations are …