Dissections or ruptures of aortic aneurysms remain a leading cause of death in the
developed world, with the majority of deaths being preventable if individuals at risk are …

Aneurysms are characterized by structural deterioration of the vascular wall leading to
progressive dilatation and, potentially, rupture of the aorta. While aortic aneurysms often …

Aortic aneurysms are an important cause of cardiovascular death in elderly patients. At
present, little is known of the pathobiology of aneurysmal disease and this limits the ability to …

Aortic aneurysms are a complex genetic disorder with known environmental risk factors such
as smoking. Along the length of the aorta, significant heterogeneity occurs in the distribution …

Genetics of abdominal aortic aneurysm : Current Opinion in Cardiology Genetics of abdominal
aortic aneurysm : Current Opinion in Cardiology Log in or Register Subscribe to journalSubscribe …

Thoracic aortic aneurysm is a potentially life-threatening condition in that it places patients at
risk for aortic dissection or rupture. However, our modern understanding of the pathogenesis …

Background: Thoracic aortic aneurysms progressively enlarge and predispose to acute
aortic dissections. Up to 25% of individuals with thoracic aortic disease harbor an underlying …

Aortic disease has many forms including aortic aneurysm and dissection, aortic coarctation
or abnormalities in aortic function, such as loss of aortic distensibility. Genetic analysis in …

Genetic studies over the past several decades have helped to better elucidate the genomics
and inheritance of thoracic aortic diseases. Seminal work from various researchers have …

Genetic predisposition and risk factors such as hypertension and smoking can instigate the
development of thoracic aortic aneurysm (TAA), which can lead to highly lethal aortic wall …