Abstract Alcohol Use Disorder (AUD) affects around 14.5 million individuals in the United
States, with Substance Use Disorder (SUD) affecting an additional 8.3 million individuals …

Stress and anxiety play an important role in the development and maintenance of drug and
alcohol addiction. The bed nucleus of the stria terminalis (BNST), a brain region involved in …

The juxtacapsular nucleus of the anterior division of the BNST (jcBNST) receives robust
glutamatergic projections from the basolateral nucleus of the amygdala (BLA), the …

There is a growing body of evidence that suggests that stress and anxiety can influence the
development of alcohol use disorders. This influence is believed to be due in part to …

A growing literature suggests that catecholamines and corticotropin-releasing factor (CRF)
interact in a serial manner to activate the bed nucleus of the stria terminalis (BNST) to drive …

The bed nucleus of the stria terminalis was first described nearly a century ago and has
since emerged as a region central to motivated behavior and affective states. The last …

The bed nucleus of the stria terminalis (BNST) is widely acknowledged as a brain structure
that regulates stress and anxiety states, as well as aversive and appetitive behaviours. The …

The bed nucleus of the stria terminalis (BNST) is a heterogeneous and complex limbic
forebrain structure, which plays an important role in controlling autonomic, neuroendocrine …

Background Anxiety during early alcohol abstinence, likely resulting from neural changes
caused by chronic alcohol use, contributes to high relapse rates. Studies in rodents show …

Complex motivated behavioral processes, such as those that can go awry following
substance abuse and other neuropsychiatric disorders, are mediated by a distributive …