INTRODUCTION DNA microarray‐based studies report differentially methylated positions
(DMPs) in blood between late‐onset dementia due to Alzheimer's disease (AD) and …

Background Alzheimer's disease affects~ 13% of people in the United States 65 years and
older, making it the most common neurodegenerative disorder. Recent work has identified …

Late-onset Alzheimer's disease (AD) is a complex age-related neurodegenerative disorder
that likely involves epigenetic factors. To better understand the epigenetic state associated …

Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by the
progressive accumulation of amyloid-beta and neurofibrillary tangles of tau in the neocortex …

To better understand DNA methylation in Alzheimer's disease (AD) from both mechanistic
and biomarker perspectives, we performed an epigenome-wide meta-analysis of blood DNA …

Background Epigenome-wide association studies (EWAS) based on human brain samples
allow a deep and direct understanding of epigenetic dysregulation in Alzheimer's disease …

Background Alterations in DNA methylation have been suggested to occur at a global,
nuclear scale or in certain loci in the context of Alzheimer's disease. Here, leveraging new …

Epigenome-wide association studies of Alzheimer's disease have highlighted
neuropathology-associated DNA methylation differences, although existing studies have …

Introduction Dementia pathogenesis begins years before clinical symptom onset,
necessitating the understanding of premorbid risk mechanisms. Here we investigated …

Recent methylome-wide association studies (MWAS) in humans have solidified the concept
that aberrant DNA methylation is associated with Alzheimer's disease (AD). We summarize …