[HTML][HTML] An overview of human single-cell RNA sequencing studies in neurobiological disease
Neurobiological disorders are highly prevalent medical conditions that contribute to
significant morbidity and mortality. Single-cell RNA sequencing (scRNA-seq) is a technique …
significant morbidity and mortality. Single-cell RNA sequencing (scRNA-seq) is a technique …
Single-cell RNA sequencing: unraveling the brain one cell at a time
D Ofengeim, N Giagtzoglou, D Huh, C Zou… - Trends in molecular …, 2017 - cell.com
Single-cell RNA sequencing (scRNA-seq) is an exciting new technology allowing the
analysis of transcriptomes from individual cells, and is ideally suited to address the inherent …
analysis of transcriptomes from individual cells, and is ideally suited to address the inherent …
Single-cell RNA-sequencing of the brain
Single-cell RNA-sequencing (scRNA-seq) is revolutionizing our understanding of the
genomic, transcriptomic and epigenomic landscapes of cells within organs. The mammalian …
genomic, transcriptomic and epigenomic landscapes of cells within organs. The mammalian …
Elucidating the cellular dynamics of the brain with single-cell RNA sequencing
A Cardona-Alberich, M Tourbez, SF Pearce… - RNA biology, 2021 - Taylor & Francis
Single-cell RNA-sequencing (scRNA-seq) has emerged in recent years as a breakthrough
technology to understand RNA metabolism at cellular resolution. In addition to allowing new …
technology to understand RNA metabolism at cellular resolution. In addition to allowing new …
RNA sequencing in post‐mortem human brains of neuropsychiatric disorders
C Wu, RM Bendriem, SP Garamszegi… - Psychiatry and …, 2017 - Wiley Online Library
RNA sequencing (RNA‐Seq), a revolutionary tool for transcriptome profiling, is becoming
increasingly important for neuroscientists in studying the transcriptional landscape of the …
increasingly important for neuroscientists in studying the transcriptional landscape of the …
Biological and medical importance of cellular heterogeneity deciphered by single-cell RNA sequencing
RK Gupta, J Kuznicki - Cells, 2020 - mdpi.com
The present review discusses recent progress in single-cell RNA sequencing (scRNA-seq),
which can describe cellular heterogeneity in various organs, bodily fluids, and pathologies …
which can describe cellular heterogeneity in various organs, bodily fluids, and pathologies …
Single-cell and single-nuclei RNA sequencing as powerful tools to decipher cellular heterogeneity and dysregulation in neurodegenerative diseases
R Cuevas-Diaz Duran, JC González-Orozco… - Frontiers in Cell and …, 2022 - frontiersin.org
Neurodegenerative diseases affect millions of people worldwide and there are currently no
cures. Two types of common neurodegenerative diseases are Alzheimer's (AD) and …
cures. Two types of common neurodegenerative diseases are Alzheimer's (AD) and …
[HTML][HTML] Single-cell RNA sequencing and its applications in the study of psychiatric disorders
ASLM Antunes, D Martins-de-Souza - Biological Psychiatry Global Open …, 2023 - Elsevier
Neuroscience is currently one of the most challenging research fields owing to the
enormous complexity of the mammalian nervous system. We are yet to understand precise …
enormous complexity of the mammalian nervous system. We are yet to understand precise …
Beyond bulk: a review of single cell transcriptomics methodologies and applications
A Kulkarni, AG Anderson, DP Merullo… - Current opinion in …, 2019 - Elsevier
Highlights•Technologies such as single-cell RNA sequencing have rapidly progressed in
recent years.•Various methods exist for preparing libraries for sequencing, each with its own …
recent years.•Various methods exist for preparing libraries for sequencing, each with its own …
Data analysis guidelines for single-cell RNA-seq in biomedical studies and clinical applications
M Su, T Pan, QZ Chen, WW Zhou, Y Gong, G Xu… - Military Medical …, 2022 - Springer
The application of single-cell RNA sequencing (scRNA-seq) in biomedical research has
advanced our understanding of the pathogenesis of disease and provided valuable insights …
advanced our understanding of the pathogenesis of disease and provided valuable insights …
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