Calcium oxalate monohydrate (COM) crystals bind avidly to the surface of proliferating and
migrating renal endothelial cells, and oxalate-induced peroxidative injury can promote …

Adhesion of calcium oxalate (CaOx) crystals to kidney cells may be a key event in the
pathogenesis of kidney stones associated with marked hyperoxaluria. Previously, we found …

Calcium oxalate monohydrate (COM) crystals bind avidly to the surface of proliferating and
migrating renal endothelial cells, perhaps a key event in kidney stone formation. Oxalate …

Abstract Epigallocatechin-3-gallate (EGCG), a predominant phytochemical in tea plant, has
been reported to prevent kidney stone formation but with vague mechanism. We …

C an glycosaminoglycans(GAGS) and semisyn-thetic sulfated polysaccharides (SSPs) be
used for the prevention of calcium oxalate stone formation? Tested in numerous …

Purpose: We studied the effect of polysaccharides on interactions between calcium oxalate
monohydrate (COM) crystals and cultured renal cells. Materials and Methods: Monolayers of …

Hyaluronic acid (HA), a macromolecule in glycosaminoglycans family, is normally excreted
into the urine with a small amount, but with much greater level in the urine from stone …

The inhibition of cell surface crystal adhesion and an appropriate increase in crystal
endocytosis contribute to the inhibition of kidney stone formation. In this study, we …

Objective: To determine the roles of endogenous cyclooxygenase 2 and prostaglandin E2 in
crystal‐cell binding, which is considered to be an important step in the development of …

Crystal retention on tubular cell surface inside renal tubules is considered as the earliest
and crucial step for kidney stone formation. Therapeutics targeting this step would cease the …