The role of adult hippocampal neurogenesis in brain health and disease
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …
Adult hippocampal neurogenesis: regulation, functional implications, and contribution to disease pathology
DT Balu, I Lucki - Neuroscience & Biobehavioral Reviews, 2009 - Elsevier
It is now well established that the mammalian brain has the capacity to produce new
neurons into adulthood. One such region that provides the proper milieu to sustain …
neurons into adulthood. One such region that provides the proper milieu to sustain …
Adult neurogenesis, mental health, and mental illness: hope or hype?
Psychiatric and neurologic disorders take an enormous toll on society. Alleviating the
devastating symptoms and consequences of neuropsychiatric disorders such as addiction …
devastating symptoms and consequences of neuropsychiatric disorders such as addiction …
Adult neurogenesis contributes to hippocampal plasticity
Adult hippocampal neurogenesis is the process by which new functional neurons are added
to the adult dentate gyrus of the hippocampus. Animal studies have shown that the degree of …
to the adult dentate gyrus of the hippocampus. Animal studies have shown that the degree of …
Adult hippocampal neurogenesis and aging
F Klempin, G Kempermann - European archives of psychiatry and clinical …, 2007 - Springer
The demographic changes in the foreseeable future stress the need for research on
successful cognitive aging. Advancing age constitutes a primary risk factor for disease of the …
successful cognitive aging. Advancing age constitutes a primary risk factor for disease of the …
Born this way: Hippocampal neurogenesis across the lifespan
The capability of the mammalian brain to generate new neurons through the lifespan has
gained much attention for the promise of new therapeutic possibilities especially for the …
gained much attention for the promise of new therapeutic possibilities especially for the …
Adult hippocampal neurogenesis: regulation and possible functional and clinical correlates
P Baptista, JP Andrade - Frontiers in neuroanatomy, 2018 - frontiersin.org
The formation of new neurons in the adult central nervous system (CNS) has been
recognized as one of the major findings in neuroanatomical research. The hippocampal …
recognized as one of the major findings in neuroanatomical research. The hippocampal …
Functional role of adult hippocampal neurogenesis as a therapeutic strategy for mental disorders
H Jun, S Mohammed Qasim Hussaini… - Neural …, 2012 - Wiley Online Library
Adult neurogenesis, the process of generating new neurons from neural stem cells, plays
significant roles in synaptic plasticity, memory, and mood regulation. In the mammalian …
significant roles in synaptic plasticity, memory, and mood regulation. In the mammalian …
The contribution of failing adult hippocampal neurogenesis to psychiatric disorders
G Kempermann, J Krebs, K Fabel - Current opinion in psychiatry, 2008 - journals.lww.com
Failing adult hippocampal neurogenesis may not explain major depression, addiction or
schizophrenia, but contributes to the hippocampal aspects of the disease. We propose that …
schizophrenia, but contributes to the hippocampal aspects of the disease. We propose that …
Hippocampal neurogenesis: regulation by stress and antidepressants
A Dranovsky, R Hen - Biological psychiatry, 2006 - Elsevier
Accumulating evidence implicates hippocampal neurogenesis in the pathophysiology of
depression. Psychosocial stress reduces neurogenesis in rodents, whereas chronic …
depression. Psychosocial stress reduces neurogenesis in rodents, whereas chronic …