The emergence of antibiotic tolerance (prolonged survival against exposure) in natural
bacterial populations is a major concern. Since it has been studied primarily in isogenic …

Bacteria are single-celled organisms, but the survival of microbial communities relies on
complex dynamics at the molecular, cellular, and ecosystem scales. Antibiotic resistance, in …

Cooperation between microbes can enable microbial communities to survive in harsh
environments. Enzymatic deactivation of antibiotics, a common mechanism of antibiotic …

Accumulating evidence suggests that the response of bacteria to antibiotics is significantly
affected by the presence of other interacting microbes. These interactions are not typically …

Genetically susceptible bacteria can escape the action of bactericidal antibiotics through
antibiotic tolerance or persistence. However, one major difference between the two …

Some bacterial resistance mechanisms degrade antibiotics, potentially protecting
neighbouring susceptible cells from antibiotic exposure. We do not yet understand how such …

Bacteria are social organisms that commonly live in dense communities surrounded by a
multitude of other species. The competitive and cooperative interactions between these …

Recent research has demonstrated that selection for antibiotic resistance occurs at very low
antibiotic concentrations in single-species experiments, but the relevance of these findings …

The evolution of antimicrobial resistance can be strongly affected by variations of
antimicrobial concentration. Here, we study the impact of periodic alternations of absence …

Bacteria have developed resistance against every antibiotic at a rate that is alarming
considering the timescale at which new antibiotics are developed. Thus, there is a critical …