Head and neck cancer arises from a series of molecular alterations progressive from
dysplasia to carcinoma in situ, and finally invasive carcinoma. Risk factors associated with …

Head and neck cancers represent a progressive genetic malady, with genetic aberrations
accumulating in response to carcinogen exposure. Although individual genomic aberrations …

Despite improvements in the diagnosis and management of head and neck squamous cell
carcinomas, there has been minimal increase in the long-term survival in these patients over …

Multiple genetic and epigenetic events, including the aberrant expression and function of
molecules regulating cell signaling, growth, survival, motility, angiogenesis, and cell cycle …

Molecular Aspects of Head and Neck Cancer Therapy - Hematology/Oncology Clinics Skip to
Main Content Advertisement Hematology/Oncology Clinics Log in Register Log in Subscribe …

Each year approximately 40,000 people in the United States and 500,000 people worldwide
are diagnosed with head‐and‐neck squamous cell carcinoma (HNSC). Although there have …

Head and neck squamous cell carcinomas (HNSCCs) are caused by tobacco and alcohol
consumption and by infection with high-risk types of human papillomavirus (HPV). Tumours …

Head and neck squamous cell carcinomas (SCCHN) arise in the mucosa of the upper
aerodigestive tract at multiple anatomic sites. While tobacco and alcohol exposure remain …

Head and neck squamous carcinoma (HNSCC) is the sixth most prevalent cancer and one
of the most aggressive malignancies worldwide. Despite continuous efforts to identify …

The tumor microenvironment (TME) is comprised of many different cell populations, such as
cancer-associated fibroblasts and various infiltrating immune cells, and non-cell …