[HTML][HTML] The regulatory roles of polysaccharides and ferroptosis-related phytochemicals in liver diseases

Y Ren, S Li, Z Song, Q Luo, Y Zhang, H Wang - Nutrients, 2022 - mdpi.com
Liver disease is a global health burden with high morbidity and mortality worldwide. Liver
injuries can develop into severe end-stage diseases, such as cirrhosis or hepatocellular …

Targeting ferroptosis with natural products in liver injury: new insights from molecular mechanisms to targeted therapies

Y Liang, S Qiu, Y Zou, L Luo - Phytomedicine, 2023 - Elsevier
Background Ferroptosis is a brand-new type of controlled cell death that is distinguished by
its reliance on iron and the production of lipid peroxidation. The role of ferroptosis in …

Emerging roles of ferroptosis in liver pathophysiology

KM Kim, SS Cho, SH Ki - Archives of Pharmacal Research, 2020 - Springer
Ferroptosis is a widely recognized process of regulated cell death linking redox state,
metabolism, and human health. It is considered a defense mechanism against extensive …

The emerging role of ferroptosis in various chronic liver diseases: opportunity or challenge

L Zhu, S Luo, Y Zhu, S Tang, C Li, X Jin… - Journal of …, 2023 - Taylor & Francis
Ferroptosis is a recently identified iron-dependent form of intracellular lipid peroxide
accumulation-mediated cell death. Different from other types of cell death mechanisms, it …

Ferroptosis as a new therapeutic opportunity for nonviral liver disease

M Jia, H Zhang, Q Qin, Y Hou, X Zhang, D Chen… - European Journal of …, 2021 - Elsevier
Nonviral liver disease is a global public health problem due to its high mortality and
morbidity. However, its underlying mechanism is unclear. Ferroptosis is a novel form of cell …

[HTML][HTML] Ferroptosis as an emerging therapeutic target in liver diseases

Y Lu, J Hu, L Chen, S Li, M Yuan, X Tian… - Frontiers in …, 2023 - frontiersin.org
Ferroptosis is an iron-dependently nonapoptotic cell death characterized by excessive
accumulation of lipid peroxides and cellular iron metabolism disturbances. Impaired iron …

[HTML][HTML] The emerging role of ferroptosis in liver diseases

S Chen, J Zhu, X Zang, Y Zhai - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Ferroptosis is a newly discovered type of cell death mediated by iron-dependent lipid
peroxide. The disturbance of iron metabolism, imbalance of the amino acid antioxidant …

Dissecting the potential role of ferroptosis in liver diseases: an updated review

G Guo, W Yang, C Sun, X Wang - Free radical research, 2023 - Taylor & Francis
Ferroptosis is a novel form of cell death, manifested by iron-dependent, non-apoptotic
manner resulting from the intracellular accumulation of large clusters of reactive oxygen …

[HTML][HTML] Targeting ferroptosis, a novel programmed cell death, for the potential of alcohol-related liver disease therapy

JF Shi, Y Liu, Y Wang, R Gao, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Ferroptosis is a new iron-dependent cell death mode, which is different from the other types
of programmed cell death, such as apoptosis, necrosis, and autophagy. Ferroptosis is …

[HTML][HTML] The advancements in targets for ferroptosis in liver diseases

X Xiang, J Gao, D Su, D Shi - Frontiers in Medicine, 2023 - frontiersin.org
Ferroptosis is a type of regulated cell death caused by iron overload and lipid peroxidation,
and at its core is an imbalance of redox reactions. Recent studies showed that ferroptosis …