The detachable dissolving microneedles (DDMNs) feature an array of needles capable of
being separated from the base sheet during administration. Here they were fabricated to …

It's of great significance to develop insulin-loaded dissolving microneedles (MNs) which are
fabricated with various methods and materials for transdermal delivery of insulin to …

Recently, numerous transdermal drug delivery systems have been developed for safe and
efficient delivery of biopharmaceuticals. Dissolving microneedles (DMNs) are one such drug …

Two-layered dissolving microneedles (DMs) containing intermediate-acting insulin,
protamine sulfate insulin (PSI), were prepared. Then a pharmacodynamic study was …

Microneedle patch (MNP) has become a hot research topic in the field of transdermal drug
delivery due to its ability to overcome the stratum corneum barrier. Among the various types …

Dissolving microneedles (MNs) display high efficiency in delivering poorly permeable drugs
and vaccines. Here, two‐layer dissolving polymeric MN patches composed of gelatin and …

This study presents a dissolving microneedle patch, composed of starch and gelatin, for the
rapid and efficient transdermal delivery of insulin. The microneedles completely dissolve …

Dissolving microneedles have been employed as a safe and convenient transdermal
delivery system for drugs and vaccines. To improve effective drug delivery, a multilayered …

Diabetes patients cannot complete effective blood glucose regulation due to their impaired
pancreatic function. At present, subcutaneous insulin injection is the only treatment for …

Purpose Dissolving microneedle patches are attracting attention as they are associated with
improved patient compliance and safety. Methods This study fabricated dissolving …