Spermatogonial stem cell self-renewal and development

M Kanatsu-Shinohara… - Annual review of cell and …, 2013 - annualreviews.org
Spermatogenesis originates from spermatogonial stem cells (SSCs). Development of the
spermatogonial transplantation technique in 1994 provided the first functional assay to …

Conservation of spermatogonial stem cell self-renewal signaling between mouse and rat

BY Ryu, H Kubota, MR Avarbock… - Proceedings of the …, 2005 - National Acad Sciences
Self-renewal of spermatogonial stem cells (SSCs) is the foundation for maintenance of
spermatogenesis throughout life in males and for continuation of a species. The molecular …

Identifying genes important for spermatogonial stem cell self-renewal and survival

JM Oatley, MR Avarbock, AI Telaranta… - Proceedings of the …, 2006 - National Acad Sciences
Spermatogonial stem cells (SSCs) are the foundation for spermatogenesis and, thus,
preservation of a species. Because of stem cell rarity, studying their self-renewal is greatly …

Serum-and feeder-free culture of mouse germline stem cells

M Kanatsu-Shinohara, K Inoue, N Ogonuki… - Biology of …, 2011 - academic.oup.com
Spermatogonial stem cells (SSCs) undergo self-renewal divisions to support
spermatogenesis. Although several in vitro SSC culture systems have been developed …

[HTML][HTML] Glial cell line-derived neurotrophic factor and endothelial cells promote self-renewal of rabbit germ cells with spermatogonial stem cell properties

H Kubota, X Wu, SM Goodyear, MR Avarbock… - The FASEB …, 2011 - ncbi.nlm.nih.gov
Previous studies suggest that exogenous factors crucial for spermatogonial stem cell (SSC)
self-renewal are conserved among several mammalian species. Since glial cell line-derived …

Spermatogonial stem cells

H Kubota, RL Brinster - Biology of reproduction, 2018 - academic.oup.com
Spermatogonial stem cells (SSCs) are the most primitive spermatogonia in the testis and
have an essential role to maintain highly productive spermatogenesis by self-renewal and …

Culture of rodent spermatogonial stem cells, male germline stem cells of the postnatal animal

H Kubota, RL Brinster - Methods in cell biology, 2008 - Elsevier
Spermatogonial stem cells (SSCs), postnatal male germline stem cells, are the foundation of
spermatogenesis, during which an enormous number of spermatozoa is produced daily by …

Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells

H Kubota, MR Avarbock… - Proceedings of the …, 2004 - National Acad Sciences
Spermatogonial stem cells (SSCs) self-renew and produce large numbers of committed
progenitors that are destined to differentiate into spermatozoa throughout life. However, the …

Glial cell line-derived neurotrophic factor regulation of genes essential for self-renewal of mouse spermatogonial stem cells is dependent on Src family kinase …

JM Oatley, MR Avarbock, RL Brinster - Journal of Biological Chemistry, 2007 - ASBMB
Self-renewal and differentiation by spermatogonial stem cells (SSCs) is the foundation for
continual spermatogenesis. SSC self-renewal is dependent on glial cell line-derived …

Technology Insight: in vitro culture of spermatogonial stem cells and their potential therapeutic uses

H Kubota, RL Brinster - Nature Clinical Practice Endocrinology & …, 2006 - nature.com
Male germline stem cells—spermatogonial stem cells (SSCs)—self-renew and produce
large numbers of differentiating germ cells that become spermatozoa throughout postnatal …