Several weeks after porcine retinal pigment epithelial (RPE) cell cultures attain confluence,
macroscopically visible brown foci appear. The cuboidal cells that form the foci contain …

The retinal pigment epithelium contains melanin and lipofuscin. It is believed that in the in
vivo system, the incomplete degradation of phagocytosed outer segment discs leads to the …

The retinal pigment epithelium contains three major types of pigment granules;
melanosomes, lipofuscin and melanolipofuscin. Melanosomes in the retinal pigment …

Cultured human retinal pigment epithelial (RPE) cells readily ingested both melanin and
lipofuscin isolated from human RPE cells. Up to 7 days post-challenge ingested granules …

1. The ultrastructure of the retinal pigment epithelium (RPE) of adult Syrian golden hamsters
and cattle was examined with respect to pigment granules and phagosomes involved in …

We compared the bovine melanotic and amelanotic retinal pigment epithelial (RPE) cells
cultivated in vitro using a number of parameters. Both cell types could be readily harvested …

Electron‐microscopic study of the size of the melanosomes, the mean percentage of
melanosomal profile area (MPMA) of the cells, and the duration of melanogenesis in the …

According to a recent hypothesis the melanin granules in the retinal pigment epithelium of
mammals originate from photosensory membrane degradation. To test this hypothesis the …

Adult human retinal pigment epithelium has been enzymatically isolated and established in
tissue culture. Primary cultures survived three to six months. Occasionally, cell lines …

Chemical and morphologic studies were carried out on bovine retinal pigment epithelial
(RPE) cells that were free of contamination by outer segments or other tissues. Both …