Dry eye disease (DED) has become a globally recognized public health problem with
complex pathogenesis. Recent studies showed that oxidative stress damage and its induced …

According to the global mapping of dry eye disease (DED), nearly 5 to 50% of people suffer
from DED, and this number is on the rise. The drug of choice Cyclosporine A (CsA) exhibits …

Dry eye disease (DED) is a common and frequent ocular surface disease worldwide, which
can cause severe ocular surface discomfort and blurred vision. Inflammation and reactive …

Corneal neovascularization is a severe eye disease that is often associated with an
inflammatory cycle and increased oxidative stress. Excessive reactive oxygen species can …

Fungal keratitis is challenging to diagnose and treat and remains a significant cause of
blindness worldwide. The easiest and most common method of drug delivery for patients …

The development of topical formulations with advanced functions to overcome the poor and
sluggish permeability/bioavailability of traditional eye drops into interior of the eye is …

Introduction Cyclosporine-A (CsA) is generally used as an immunosuppressant and is also
prescribed for some ophthalmic applications such as vernal keratoconjunctivitis and dry eye …

Topical ocular drug administration aimed at providing a high drug concentration at the
precorneal site accompanied with enhanced corneal permeability to avoid systemic side …

Eye-drop formulations as conventional regimens to tackle ocular diseases are far from
efficient due to the rapid clearance by eye tears and the blockage of the corneal epithelium …

Purpose We aimed to compare the physicochemical properties and in vivo efficacy of
commercially available nanoemulsion cyclosporine A (CsA) eyedrops in benzalkonium …