This review provides a tutorial for individuals interested in quantitative veterinary
pharmacology and toxicology and offers a basis for establishing guidelines for …

Physiologically based pharmacokinetic (PBPK) models for chemicals in food animals are a
useful tool in estimating chemical tissue residues and withdrawal intervals. Physiological …

The application of mathematical modeling to problems in animal health has a rich history in
the form of pharmacokinetic modeling applied to problems in veterinary medicine. Advances …

Physiologically based kinetic (PBK) models in the 10 most common species of farm animals
were identified through an extensive literature search. This resulted in 39 PBK models …

In veterinary drug development procedures, pharmacokinetic (PK) and pharmacodynamic
(PD) data have generally been established in separate, parallel studies to assist in the …

This report is the third in a series of studies that aimed to compile physiological parameters
related to develop physiologically based pharmacokinetic (PBPK) models for drugs and …

The environmental fates of pharmaceuticals and the effects of crop protection products on
non-target species are subjects that are undergoing intense review. Since measuring the …

A common feature of human and veterinary pharmacokinetics is the importance of
identifying and quantifying the key determinants of between‐patient variability in drug …

In today's pharmaceutical research and development, physiologically-based
pharmacokinetic (PBPK) modeling plays an important role in the design, evaluation and …

Population pharmacokinetics can be defined as a study of the basic features of drug
disposition in a population, accounting for the influence of diverse pathophysiological factors …