The double-stranded RNA-dependent protein kinase PKR plays multiple roles in cells, in
response to different stress situations. As a member of the interferon (IFN)‑Stimulated …

The double stranded RNA (dsRNA)-activated protein kinase PKR is a ubiquitously
expressed serine/threonine protein kinase that is induced by interferon and activated by …

The double-stranded RNA-dependent protein kinase PKR is a critical mediator of the
antiproliferative and antiviral effects exerted by interferons. Not only is PKR an effector …

The IFN-induced double-stranded RNA-dependent protein kinase (PKR) is one of the four
mammalian serine-threonine kinases (the three others being HRI, GCN2 and PERK) that …

The double-stranded (ds) RNA-dependent protein kinase (PKR) regulates protein synthesis
by phosphorylating the α subunit of eukaryotic initiation factor-2. PKR is activated by viral …

The interferon-inducible double-stranded RNA (dsRNA)-activated protein kinase, PKR,
plays an important role in messenger (m) RNA translation by phosphorylating the α subunit …

The double-stranded (ds) RNA-activated protein kinase, PKR, has a key role in the innate
immunity response to viral infection in higher eukaryotes. PKR contains an N-terminal …

Cellular recognition of foreign dsRNA species is an important component of host defense,
responsible for initiating innate immune responses to virus infection. Over the years, a …

The interferon (IFN)-induced, double-stranded (ds) RNA-activated serine-threonine protein
kinase, PKR, is a key mediator of the antiviral activities of IFNs. In addition, PKR activity is …

Protein kinase PKR is an interferon‐induced enzyme that plays a key role in the control of
viral infections and cellular homeostasis. Compared with other known kinases, PKR is …