Vascular network engineering is essential for nutrient delivery to tissue-engineered
constructs and, consequently, their survival. In addition, the functionality of tissues also …

A promising approach to overcome hypoxic conditions in tissue engineered constructs is to
use the potential of endothelial cells (EC) to form networks in vitro when co-cultured with a …

Vascularization of tissue-engineered constructs is essential to provide sufficient nutrient
supply and hemostasis after implantation into target sites. Co-cultures of adipose-derived …

The knowledge of the blood microvasculature and its functional role in health and disease
has grown significantly attributable to decades of research and numerous advances in cell …

In vitro endothelial cell organization into capillaries is a long standing challenge of tissue
engineering. We recently showed the utility of low level interstitial flow in guiding the …

Neovascularization of adipose tissue equivalents is a crucial step in successful adipose
tissue engineering, since insufficient vascularization results in graft resorption in an in vivo …

Background Co-cultures of endothelial cells with mesenchymal stem cells currently
represent one of the most promising approaches in providing oxygen and nutrient supply for …

Vascularization of engineered tissues is one of the current challenges in tissue engineering.
Several strategies aim to generate a prevascularized scaffold which can be implanted at …

The vasculature is an essential, physiological element in virtually all human tissues.
Formation of perfusable vasculature is therefore crucial for reliable tissue modeling. Three …

The lymphatic system is involved in various biological processes, including fluid transport
from the interstitium into the venous circulation, lipid absorption, and immune cell trafficking …