Seizure is paroxysmal abnormal electrical discharges in the cerebral cortex. Inflammatory
pathways and oxidative stress are involved in the pathophysiology of seizures. Stress can …

Epilepsy is a chronic neurological condition that affects 1%–2% of the world population.
Although research about the disease is advancing and a wide variety of drugs is available …

A growing body of evidence suggests that stress triggers a variety of pathophysiological
responses. Recent studies show that stress produces enduring effects on structure and …

Epilepsy is a disease which affects between 1 and 2% of the population, and a large
proportion of these people do not react to currently available anticonvulsant medications …

The oxidative/antioxidative status was investigated in maximal electroshock-induced
seizures in mice, a well established model of generalized seizures in humans. Mice were …

Electroconvulsive therapy has been used in the treatment of psychiatric disorders since the
1930s, but little progress has been made in understanding the cellular mechanisms …

Epilepsy is a chronic neurological disease with recurrent seizures. Increasing evidence
suggests that endoplasmic reticulum (ER) stress may play a role in the pathogenesis of …

Background Neuroinflammation with activation of microglia and production of
proinflammatory cytokines in the brain plays an active role in epileptic disorders. Brain …

Background: Frequent seizure is followed by overproduction of free radicals and brain
oxidative stress. Renin angiotensin system (RAS) has some effects on central nervous …

Inflammation has been identified as an important mediator of seizures and epileptogenesis.
Understanding the mechanisms underlying seizure-induced neuroinflammation could lead …