Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus

C Schmidt-Hieber, P Jonas, J Bischofberger - Nature, 2004 - nature.com
Neural stem cells in various regions of the vertebrate brain continuously generate neurons
throughout life,,,. In the mammalian hippocampus, a region important for spatial and …

Functional neurogenesis in the adult hippocampus

H Van Praag, AF Schinder, BR Christie, N Toni… - Nature, 2002 - nature.com
There is extensive evidence indicating that new neurons are generated in the dentate gyrus
of the adult mammalian hippocampus, a region of the brain that is important for learning and …

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

SF Sorrells, MF Paredes, A Cebrian-Silla, K Sandoval… - Nature, 2018 - nature.com
New neurons continue to be generated in the subgranular zone of the dentate gyrus of the
adult mammalian hippocampus,,,,. This process has been linked to learning and memory …

More hippocampal neurons in adult mice living in an enriched environment

G Kempermann, HG Kuhn, FH Gage - Nature, 1997 - nature.com
Neurogenesis occurs in the dentate gyrus of the hippocampus throughout the life of a
rodent1–4, but the function of these new neurons and the mechanisms that regulate their …

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

A Sahay, KN Scobie, AS Hill, CM O'Carroll… - Nature, 2011 - nature.com
Adult hippocampal neurogenesis is a unique form of neural circuit plasticity that results in
the generation of new neurons in the dentate gyrus throughout life,. Neurons that arise in …

Unique processing during a period of high excitation/inhibition balance in adult-born neurons

A Marín-Burgin, LA Mongiat, MB Pardi, AF Schinder - Science, 2012 - science.org
The adult dentate gyrus generates new granule cells (GCs) that develop over several weeks
and integrate into the preexisting network. Although adult hippocampal neurogenesis has …

Restoring production of hippocampal neurons in old age

HA Cameron, RDG McKay - Nature neuroscience, 1999 - nature.com
The production of hippocampal granule neurons continues throughout adulthood but
dramatically decreases in old age. Here we show that reducing corticosteroid levels in aged …

Neurogenesis in the adult is involved in the formation of trace memories

TJ Shors, G Miesegaes, A Beylin, M Zhao, T Rydel… - Nature, 2001 - nature.com
The vertebrate brain continues to produce new neurons throughout life,,,,,,,,,,,. In the rat
hippocampus, several thousand are produced each day, many of which die within weeks …

Latent synaptic pathways revealed after tetanic stimulation in the hippocampus

R Miles, RKS Wong - Nature, 1987 - nature.com
Synaptic plasticity may result from changes at existing synapses or from alterations in the
number of functional synaptic connections1. In the hippocampus excitatory synaptic strength …

Learning enhances adult neurogenesis in the hippocampal formation

E Gould, A Beylin, P Tanapat, A Reeves… - Nature neuroscience, 1999 - nature.com
Thousands of hippocampal neurons are born in adulthood, suggesting that new cells could
be important for hippocampal function. To determine whether hippocampus-dependent …