[HTML][HTML] Plasmalogens, the vinyl ether-linked glycerophospholipids, enhance learning and memory by regulating brain-derived neurotrophic factor
MS Hossain, S Mawatari, T Fujino - Frontiers in Cell and …, 2022 - frontiersin.org
Plasmalogens (Pls), a kind of glycerophospholipids, have shown potent biological effects
but their role in hippocampus-dependent memory remained mostly elusive. Here, we first …
but their role in hippocampus-dependent memory remained mostly elusive. Here, we first …
Reduction of ether-type glycerophospholipids, plasmalogens, by NF-κB signal leading to microglial activation
Neuroinflammation characterized by activation of glial cells is observed in various
neurodegenerative diseases including Alzheimer's disease (AD). Although the reduction of …
neurodegenerative diseases including Alzheimer's disease (AD). Although the reduction of …
[HTML][HTML] Plasmalogens eliminate aging-associated synaptic defects and microglia-mediated neuroinflammation in mice
J Gu, L Chen, R Sun, JL Wang, J Wang… - Frontiers in Molecular …, 2022 - frontiersin.org
Neurodegeneration is a pathological condition in which nervous system or neuron losses its
structure, function, or both leading to progressive neural degeneration. Growing evidence …
structure, function, or both leading to progressive neural degeneration. Growing evidence …
[HTML][HTML] Plasmalogens inhibit neuroinflammation and promote cognitive function
MS Hossain, S Mawatari, T Fujino - Brain Research Bulletin, 2023 - Elsevier
Neuroinflammation (NF) is defined as the activation of brain glial cells that are found in
neurodegenerative diseases including Alzheimer's disease (AD). It has been known that an …
neurodegenerative diseases including Alzheimer's disease (AD). It has been known that an …
PUFA-plasmalogens attenuate the LPS-induced nitric oxide production by inhibiting the NF-kB, p38 MAPK and JNK pathways in microglial cells
M Youssef, A Ibrahim, K Akashi, MS Hossain - Neuroscience, 2019 - Elsevier
The special lipids plasmalogens (Pls) were reported to be reduced in the neurodegenerative
brains such as Alzheimer's disease where a marked increase of glial activation is often …
brains such as Alzheimer's disease where a marked increase of glial activation is often …
Neuronal orphan G-protein coupled receptor proteins mediate plasmalogens-induced activation of ERK and Akt signaling
MS Hossain, K Mineno, T Katafuchi - PloS one, 2016 - journals.plos.org
The special glycerophospholipids plasmalogens (Pls) are enriched in the brain and reported
to prevent neuronal cell death by enhancing phosphorylation of Akt and ERK signaling in …
to prevent neuronal cell death by enhancing phosphorylation of Akt and ERK signaling in …
Biological functions of plasmalogens
MS Hossain, S Mawatari, T Fujino - Peroxisome biology: Experimental …, 2020 - Springer
Plasmalogens (Pls) are one kind of phospholipids enriched in the brain and other organs.
These lipids were thought to be involved in the membrane bilayer formation and anti-oxidant …
These lipids were thought to be involved in the membrane bilayer formation and anti-oxidant …
EPA-enriched ethanolamine plasmalogen and EPA-enriched phosphatidylethanolamine enhance BDNF/TrkB/CREB signaling and inhibit neuronal apoptosis in vitro …
H Che, L Zhang, L Ding, W Xie, X Jiang, C Xue… - Food & function, 2020 - pubs.rsc.org
Our previous study showed that EPA-enriched ethanolamine plasmalogen (EPA-pPE)
exerted more significant effects than EPA-enriched phosphatidylethanolamine (EPA-PE) in …
exerted more significant effects than EPA-enriched phosphatidylethanolamine (EPA-PE) in …
Plasmalogens rescue neuronal cell death through an activation of AKT and ERK survival signaling
MS Hossain, M Ifuku, S Take, J Kawamura, K Miake… - PloS one, 2013 - journals.plos.org
Neuronal cells are susceptible to many stresses, which will cause the apoptosis and
neurodegenerative diseases. The precise molecular mechanism behind the neuronal …
neurodegenerative diseases. The precise molecular mechanism behind the neuronal …
[HTML][HTML] Protect effects of seafood-derived plasmalogens against amyloid-beta (1–42) induced toxicity via modulating the transcripts related to endocytosis, autophagy …
J Feng, G Song, Q Shen, X Chen, Q Wang… - Frontiers in aging …, 2021 - frontiersin.org
To investigate the underlying mechanisms of decreased plasmalogens (Pls) levels in
neurodegenerative diseases, here the effects of seafood-derived Pls on undifferentiated and …
neurodegenerative diseases, here the effects of seafood-derived Pls on undifferentiated and …