The present study aims to directly investigate the behavioral and antioxidant effects of
simvastatin in a model of bipolar mania induced by lisdexamfetamine dimesylate. Wistar rats …

抄録 We investigated the in vitro superoxide anion scavenging activities of fluvastatin and its
metabolites. Fluvastatin showed dose-dependent superoxide anion scavenging activity in …

AIMS: Beneficial effects of statin treatment on cardiovascular morbidity and mortality has
been not entirely explained by the reduction in LDL-cholesterol level. We hypothesised that …

This study was an attempt to establish the extent of increased oxidative stress in
hypercholesterolemic patients and to evaluate the effect of atorvastatin on the oxidative …

Background: Treatment of hypercholesterolemia with statins is remarkably effective in
cardiovascular prevention. This has led to the hypothesis that these drugs may act on the …

Lisdexamfetamine dimesylate (LDX) is a prodrug that requires conversion to d-
amphetamine (d-AMPH) for bioactivity. Treatment with d-AMPH induces hyperlocomotion …

Atherosclerosis is a chronic inflammatory disease of multiple etiologies. It is associated with
the accumulation of oxidized lipids in arterial lesions leading to coronary heart disease. 3 …

The combination of amlodipine with atorvastatin metabolite shows a synergistic antioxidant
effect on lipid peroxidation in human low-density lipoproteins and membrane vesicles …

Bipolar disorder is a chronic disease characterized by recurring episodes of mania and
depression that can lead to disability. This study investigates the protective effects of …

Free radicals generated from oxidative stress (OS) have been depicted in the causation of
cancerous and noncancerous diseases in humans. Increase in fat content of the body may …