The efficacy of Roux-en-Y gastric-bypass (RYGB) and other bariatric surgeries in the
management of obesity and type 2 diabetes mellitus and novel developments in …

Cholecystokinin (CCK), peptide YY (PYY), and ghrelin have been proposed to act as satiety
hormones. CCK and PYY are stimulated during meal intake by the presence of nutrients in …

Emerging evidence has suggested a possible physiologic role for peripheral glucagon-like
peptide 1 (GLP-1) in regulating glucose metabolism and food intake. The likely site of action …

Context: The relationship between postprandial peptides at circulating physiological levels
and short-term appetite control is not well understood. Objective: The purpose of this study …

The global obesity epidemic has resulted in significant morbidity and mortality. However, the
medical treatment of obesity is limited. Gastric bypass is an effective surgical treatment but …

GLP-1 is a gastrointestinal L-cell hormone that enhances glucose-stimulated insulin
secretion. Hence, strategies that prevent GLP-1 degradation or activate the GLP-1 receptor …

Ghrelin, identified as an endogenous ligand for the growth hormone secretagogue receptor,
functions as a somatotrophic and orexigenic signal from the stomach. Ghrelin has a unique …

Obesity and type II diabetes mellitus have reached epidemic proportions. From this
perspective, knowledge about the regulation of satiety and food intake is more important …

Objective The hormones glucagon-like peptide 1 (GLP-1), peptide YY3-36 (PYY3–36),
ghrelin, glucose-dependent insulinotropic polypeptide (GIP) and glucagon have all been …

Ghrelin is an enteric peptide that is the only known circulating appetite stimulant. This
feature of the hormone has garnered widespread attention, as reflected by more than 1000 …