[PDF][PDF] MAJOR ARTICLE

Y Huang, A Abdelgawad, A Turchinovich, S Queen… - 2023 - researchgate.net
Methods: Postmortem occipital cortex samples were obtained from uninfected controls and
SIV-infected subjects (acute and chronic phases with or without CNS pathology (SIV …

RNA Landscapes of Brain and Brain-Derived Extracellular Vesicles in Simian Immunodeficiency Virus Infection and Central Nervous System Pathology

Y Huang, A Abdelgawad, A Turchinovich… - The Journal of …, 2024 - academic.oup.com
Background Brain tissue-derived extracellular vesicles (bdEVs) act locally in the central
nervous system (CNS) and may indicate molecular mechanisms in human …

[HTML][HTML] RNA landscapes of brain tissue and brain tissue-derived extracellular vesicles in simian immunodeficiency virus (SIV) infection and SIV-related central …

Y Huang, A Abdelgawad, A Turchinovich, S Queen… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Methods: Postmortem occipital cortex tissue were collected from pigtailed macaques:
uninfected controls and SIV-infected subjects (acute phase and chronic phase with or …

Cerebrospinal fluid HIV-1 RNA levels: correlation with HIV encephalitis

P Cinque, L Vago, D Ceresa, F Mainini, MR Terreni… - Aids, 1998 - journals.lww.com
Objective: Neuropathological abnormalities induced by HIV-1 are not always predictable on
the basis of the presence of HIV-related neurological symptoms. HIV-1 RNA load was …

Clinical importance of the quantification of HIV-1 RNA in cerebrospinal fluid for the diagnosis of HIV encephalitis

P Bossi, S Dupre, N Dupin, A Coutellier… - Pathologie …, 1998 - europepmc.org
We evaluated prospectively the HIV-1 RNA level in CSF as a marker of HIV encephalitis
diagnosis. 110 HIV-1 infected patients (mean age: 39 years; sex-ratio M/F: 94/16) were …

S100β as a novel and accessible indicator for the presence of monocyte‐driven encephalitis in AIDS

NA Renner, RK Redmann… - Neuropathology and …, 2012 - Wiley Online Library
NA Renner, RK Redmann, T. Moroney‐Rasmussen, HA Sansing, PP Aye, PJ Didier, AA
Lackner and AG MacLean (2012) Neuropathology and Applied Neurobiology38, 162–174 …

Molecular and pathologic insights from latent HIV-1 infection in the human brain

P Desplats, W Dumaop, D Smith, A Adame, I Everall… - Neurology, 2013 - AAN Enterprises
Objective: We aimed to investigate whether HIV latency in the CNS might have adverse
molecular, pathologic, and clinical consequences. Methods: This was a case-control …

Early SIV encephalopathy

B Hurtrel, L Chakrabarti, M Hurtrel… - Journal of medical …, 1991 - Wiley Online Library
SIV encephalopathy was studied in rhesus macaques early after intracerebral (IC) or
intravenous (IV) inoculation. Although SIV was detected in the brain of all IC‐inoculated …

Systematic post-mortem analysis of brain tissue from an HIV-1 subtype C viremic decedent revealed a paucity of infection and pathology

J Musumali, P Julius, SN Siyumbwa, D Yalcin… - Journal of …, 2022 - Springer
Whether the human brain is a robust reservoir for HIV-1 subtype C has yet to be established.
We aimed to determine whether HIV-1 subtype C infection can be detected in the brain …

Viral load and neuropathology in the SIV model

D Boche, E Khatissian, F Gray, P Falanga… - Journal of …, 1999 - Taylor & Francis
To investigate neuropathological processes involved in HIV infection, a longitudinal analysis
of central nervous system (CNS) changes was performed using the SIV-infected macaque …