Elevations in Creatine Kinase are Not Related to the Choice or Dose of Statins in Patients Taking Colchicine 0.5 mg Daily: Insights from the LoDoCo2 Trial
A van Broekhoven, JW Eikelboom, SM Nidorf… - Clinical Drug …, 2023 - Springer
Colchicine 0.5 mg once daily reduces the risk of major adverse cardiovascular events in
patients with coronary disease [1, 2]. The randomized trials that established the efficacy of …
patients with coronary disease [1, 2]. The randomized trials that established the efficacy of …
Colchicine gastrotoxicity in a patient with chronic kidney disease
GCH Ho, WH Lau, MH Leung - Rheumatology, 2019 - academic.oup.com
A 72-year-old man presented with upper gastrointestinal bleeding. He had hyperlipidaemia,
gout and chronic kidney disease (calculated glomerular filtration rate 22ml/min/1.73 m2) …
gout and chronic kidney disease (calculated glomerular filtration rate 22ml/min/1.73 m2) …
Is colchicine safe for cardiovascular indications?
Background Colchicine has an emerging role in the cardiovascular field (eg acute and
chronic coronary syndromes, pericarditis, atrial fibrillation), although, concerns for side …
chronic coronary syndromes, pericarditis, atrial fibrillation), although, concerns for side …
A systematic review of the drug–drug interaction between statins and colchicine: patient characteristics, etiologies, and clinical management strategies
NC Schwier, CK Cornelio… - … : The Journal of Human …, 2022 - Wiley Online Library
Colchicine and statins are frequently co‐prescribed for prevention and treatment of
cardiovascular diseases, auto‐inflammatory diseases, and gout. Both are substrates and …
cardiovascular diseases, auto‐inflammatory diseases, and gout. Both are substrates and …
[HTML][HTML] Myopathy caused by the interaction of colchicine and statins
AS Kazakov, MA Darmostukova, TM Bukatina… - Safety and Risk of …, 2018 - risksafety.ru
Myopathy is a life-threatening disease that can be caused, among other things, by the intake
of various medications. Despite the fact that many drug-induced myopathies are well known …
of various medications. Despite the fact that many drug-induced myopathies are well known …
Colchicine: An ancient drug with multiple benefits
The history of colchicine dates to ancient Egyptians when it was used for alleviation of
swelling and pain. Although its popularity varied throughout the years, colchicine has been a …
swelling and pain. Although its popularity varied throughout the years, colchicine has been a …
Single-dose, open-label study of the differences in pharmacokinetics of colchicine in subjects with renal impairment, including end-stage renal disease
Y Solak, SB Acikgoz, M Yildirim - Clinical drug investigation, 2015 - Springer
We read the article by Wason et al.[1] with great enthusiasm. The authors conducted an
elaborate study in which they investigated colchicine pharmacokinetics in subjects with …
elaborate study in which they investigated colchicine pharmacokinetics in subjects with …
Single-dose, open-label study of the differences in pharmacokinetics of colchicine in subjects with renal impairment, including end-stage renal disease
S Wason, D Mount, R Faulkner - Clinical drug investigation, 2014 - Springer
Abstract Background and Objective The effect of renal impairment on colchicine
pharmacokinetics in patients with chronic kidney disease (CKD) has not been studied …
pharmacokinetics in patients with chronic kidney disease (CKD) has not been studied …
Colchicine toxicity: an exaggerated reality?
Y Solak, SB Acikgoz, M Yildirim - The American journal of medicine, 2015 - amjmed.com
With great interest, we read the review article entitled “Colchicine: Old and New” by
Slobodnick et al. 1 The authors reviewed the general pharmacokinetic properties of …
Slobodnick et al. 1 The authors reviewed the general pharmacokinetic properties of …