Perihematomal edema after intracerebral hemorrhage: an update on pathogenesis, risk factors, and therapeutic advances

Y Chen, S Chen, J Chang, J Wei, M Feng… - Frontiers in …, 2021 - frontiersin.org
Intracerebral hemorrhage (ICH) has one of the worst prognoses among patients with stroke.
Surgical measures have been adopted to relieve the mass effect of the hematoma, and …

Perihematomal edema: implications for intracerebral hemorrhage research and therapeutic advances

M Selim, C Norton - Journal of neuroscience research, 2020 - Wiley Online Library
In humans, perihematomal edema (PHE) is considered to be a radiological marker of
secondary injury following intracerebral hemorrhage (ICH). There is also evidence that PHE …

Secondary hematoma expansion and perihemorrhagic edema after intracerebral hemorrhage: from bench work to practical aspects

K Lim-Hing, F Rincon - Frontiers in Neurology, 2017 - frontiersin.org
Intracerebral hemorrhages (ICH) represent about 10–15% of all strokes per year in the
United States alone. Key variables influencing the long-term outcome after ICH are …

Neutrophil–lymphocyte ratio and perihematomal edema growth in intracerebral hemorrhage

AM Gusdon, G Gialdini, G Kone, H Baradaran… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Although preclinical studies have shown inflammation to
mediate perihematomal edema (PHE) after intracerebral hemorrhage, clinical data are …

Perihematomal edema and functional outcomes in intracerebral hemorrhage: influence of hematoma volume and location

SB Murthy, Y Moradiya, J Dawson, KR Lees… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—Perihematomal edema (PHE) is associated with poor outcomes
after intracerebral hemorrhage (ICH). PHE evolves in the early period after ICH, providing a …

Natural history of perihematomal edema and impact on outcome after intracerebral hemorrhage

TY Wu, G Sharma, D Strbian, J Putaala, PM Desmond… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Edema may worsen outcome after intracerebral hemorrhage
(ICH). We assessed its natural history, factors influencing growth, and association with …

[HTML][HTML] Brain edema formation and therapy after intracerebral hemorrhage

Y Wan, KG Holste, Y Hua, RF Keep, G Xi - Neurobiology of disease, 2023 - Elsevier
Intracerebral hemorrhage (ICH) accounts for about 10% of all strokes in the United States of
America causing a high degree of disability and mortality. There is initial (primary) brain …

Mechanism and therapy of brain edema after intracerebral hemorrhage

H Zheng, C Chen, J Zhang, Z Hu - Cerebrovascular diseases, 2016 - karger.com
Background: Intracerebral hemorrhage (ICH) is a subtype of stroke with a severe high
mortality and disability rate and accounts for about 10-15% of all strokes. The oppression …

Association of molecular markers with perihematomal edema and clinical outcome in intracerebral hemorrhage

N Li, YF Liu, L Ma, H Worthmann, YL Wang, YJ Wang… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Perihematomal edema contributes to secondary brain injury in
intracerebral hemorrhage (ICH). Increase of matrix metalloproteinases (MMPs) and growth …

Rate of perihaematomal oedema expansion is associated with poor clinical outcomes in intracerebral haemorrhage

SB Murthy, S Urday, LA Beslow, J Dawson… - Journal of Neurology …, 2016 - jnnp.bmj.com
Background Perihaematomal edema (PHE) expansion rate may be a predictor of outcome
after intracerebral haemorrhage (ICH). We determined whether PHE expansion rate in the …