The secrets of Acinetobacter secretion

BS Weber, RL Kinsella, CM Harding, MF Feldman - Trends in microbiology, 2017 - cell.com
Infections caused by the bacterial pathogen Acinetobacter baumannii are a mounting
concern for healthcare practitioners as widespread antibiotic resistance continues to limit …

Uncovering the Secretion Systems of Acinetobacter baumannii: Structures and Functions in Pathogenicity and Antibiotic Resistance

P Li, S Zhang, J Wang, MM Al-Shamiri, B Han, Y Chen… - Antibiotics, 2023 - mdpi.com
Infections led by Acinetobacter baumannii strains are of great concern in healthcare
environments due to the strong ability of the bacteria to spread through different apparatuses …

Acinetobacter: an emerging pathogen with a versatile secretome

NM Elhosseiny, AS Attia - Emerging microbes & infections, 2018 - Taylor & Francis
Acinetobacter baumannii is a notorious pathogen that has emerged as a healthcare
nightmare in recent years because it causes serious infections that are associated with high …

Medically Relevant Acinetobacter Species Require a Type II Secretion System and Specific Membrane-Associated Chaperones for the Export of Multiple Substrates …

CM Harding, RL Kinsella, LD Palmer, EP Skaar… - PLoS …, 2016 - journals.plos.org
Acinetobacter baumannii, A. nosocomialis, and A. pittii have recently emerged as
opportunistic human pathogens capable of causing severe human disease; however, the …

Pathogenic Acinetobacter species have a functional type I secretion system and contact-dependent inhibition systems

CM Harding, MR Pulido, G Di Venanzio… - Journal of biological …, 2017 - ASBMB
Pathogenic Acinetobacter species, including Acinetobacter baumannii and Acinetobacter
nosocomialis, are opportunistic human pathogens of increasing relevance worldwide …

Genomic and Functional Analysis of the Type VI Secretion System in Acinetobacter

BS Weber, ST Miyata, JA Iwashkiw, BL Mortensen… - PloS one, 2013 - journals.plos.org
The genus Acinetobacter is comprised of a diverse group of species, several of which have
raised interest due to potential applications in bioremediation and agricultural purposes. In …

Comparative proteomics analyses of Acinetobacter baumannii strains ATCC 17978 and AB5075 reveal the differential role of type II secretion system secretomes in …

NM Elhosseiny, NB Elhezawy, AS Attia - Microbial pathogenesis, 2019 - Elsevier
Acinetobacter baumannii is an emerging nosocomial pathogen with alarming antibiotic
resistance profiles. A better understanding of the virulence and resistance mechanisms of …

The secretome of Acinetobacter baumannii ATCC 17978 type II secretion system reveals a novel plasmid encoded phospholipase that could be implicated in lung …

NM Elhosseiny, OM El-Tayeb, AS Yassin, S Lory… - International Journal of …, 2016 - Elsevier
Acinetobacter baumannii infections are compounded with a striking lack of treatment
options. In many Gram-negative bacteria, secreted proteins play an important early role in …

Genetic Dissection of the Type VI Secretion System in Acinetobacter and Identification of a Novel Peptidoglycan Hydrolase, TagX, Required for Its Biogenesis

BS Weber, SW Hennon, MS Wright, NE Scott… - MBio, 2016 - Am Soc Microbiol
The type VI secretion system (T6SS) is a widespread secretory apparatus produced by Gram-
negative bacteria that has emerged as a potent mediator of antibacterial activity during …

Acinetobacter baumannii Is Dependent on the Type II Secretion System and Its Substrate LipA for Lipid Utilization and In Vivo Fitness

TL Johnson, U Waack, S Smith, H Mobley… - Journal of …, 2016 - Am Soc Microbiol
Gram-negative bacteria express a number of sophisticated secretion systems to transport
virulence factors across the cell envelope, including the type II secretion (T2S) system …