Background. Our previous works revealed Yangjing capsule (YC) could inhibit cell
apoptosis and promote testosterone production in Leydig cells. SET protein has been …

Yangjing Capsule (YC), an innovative Chinese medicine based on traditional prescription,
promotes testosterone synthesis by upregulating the expression of steroidogenic enzymes …

The present study aims to investigate the roles of steroidogenic acute regulatory protein
(StAR) in Yangjing Capsule (YC) induced anti-apoptotic effects on Leydig cells and the …

Objectives. This study aimed to explore the effect and mechanism of Yangjing capsule on
testosterone secretion in mouse Leydig tumor cells (MLTC‐1). Methods. MLTC‐1 cells were …

Objective. To investigate the effect of Yangjing Capsule (YC) extract on proliferation of GC‐1
spermatogonia (spg) cells and the mechanism. Methods. GC‐1 spg cells were treated with …

Background. The testicular microcirculation was an important aspect of testicular physiology
and it offered a stable environment for the transport of nutrients and secretary products in the …

Approximately 40% of middle‐aged men exhibit symptoms of late‐onset hypogonadism
(LOH). However, the mechanism of androgen deficiency is still currently unclear. As shown …

Objective To investigate the therapeutic effects and pharmacological mechanisms of Yishen
Xingyang capsule (YXC) in oligoasthenospermia (OA) rats. Methods Forty-eight male …

Objective To observe the effect of Tiancan Zhuangyang Powder (TCZYP) on the
steroidogenic acute regulatory protein (stAR protein) expression of Leydig cells in model …

Objective This research aims to study the internal mechanism that promotes the testosterone
synthesis by StarD7 and Wnt/β-catenin, and explores a new regulatory pathway of …