[HTML][HTML] No evidence of brown adipose tissue activation after 24 weeks of supervised exercise training in young sedentary adults in the ACTIBATE randomized …

B Martinez-Tellez, G Sanchez-Delgado… - Nature …, 2022 - nature.com
Exercise modulates both brown adipose tissue (BAT) metabolism and white adipose tissue
(WAT) browning in murine models. Whether this is true in humans, however, has remained …

[HTML][HTML] Exercise induces white adipose tissue browning across the weight spectrum in humans

B Otero-Díaz, M Rodríguez-Flores… - Frontiers in …, 2018 - frontiersin.org
While the effect of exercise on white adipose tissue browning and metabolic improvement in
rodents is clear, there are few studies in humans with inconclusive results. Thus, the aim of …

Activating brown adipose tissue through exercise (ACTIBATE) in young adults: rationale, design and methodology

G Sanchez-Delgado, B Martinez-Tellez, J Olza… - Contemporary clinical …, 2015 - Elsevier
Aims The energy expenditure capacity of brown adipose tissue (BAT) makes it an attractive
target as a therapy against obesity and type 2 diabetes. BAT activators namely …

Decreased insulin‐stimulated brown adipose tissue glucose uptake after short‐term exercise training in healthy middle‐aged men

P Motiani, KA Virtanen, KK Motiani… - Diabetes, Obesity …, 2017 - Wiley Online Library
Aims To test the hypothesis that high‐intensity interval training (HIIT) and moderate‐intensity
continuous training (MICT) improve brown adipose tissue (BAT) insulin sensitivity …

[HTML][HTML] Effect of chronic athletic activity on brown fat in young women

V Singhal, GD Maffazioli, KE Ackerman, H Lee… - PLoS …, 2016 - journals.plos.org
Background The effect of chronic exercise activity on brown adipose tissue (BAT) is not
clear, with some studies showing positive and others showing negative associations …

Exercise-mediated effects on white and brown adipose tissue plasticity and metabolism

DM Sepa-Kishi, RB Ceddia - Exercise and sport sciences reviews, 2016 - journals.lww.com
Obesity has reached global epidemic proportions and is threatening the economic
sustainability of the health care system of many countries worldwide. This is related largely …

Association of objectively measured physical activity with brown adipose tissue volume and activity in young adults

FM Acosta, B Martinez-Tellez… - The Journal of …, 2019 - academic.oup.com
Purpose Human brown adipose tissue (BAT) has gained considerable attention as a
potential therapeutic target for obesity and type 2 diabetes; however, whether physical …

Low brown adipose tissue activity in endurance-trained compared with lean sedentary men

MJ Vosselman, J Hoeks, B Brans… - International Journal of …, 2015 - nature.com
Results: Cold-induced BAT activity was significantly lower in athletes, and no differences in
gene expression of classical brown and beige adipocyte markers were detected in …

Kinetics of human brown adipose tissue activation and deactivation

BP Leitner, LS Weiner, M Desir, PA Kahn… - International Journal of …, 2019 - nature.com
Brown adipose tissue (BAT) has been identified as a potential target in the treatment and
prevention of obesity and metabolic disease. The precise kinetics of BAT activation and the …

[HTML][HTML] Brown adipose tissue in morbidly obese subjects

GHEJ Vijgen, ND Bouvy, GJJ Teule, B Brans… - PloS one, 2011 - journals.plos.org
Background Cold-stimulated adaptive thermogenesis in brown adipose tissue (BAT) to
increase energy expenditure is suggested as a possible therapeutic target for the treatment …