Humans vary widely in their susceptibility to tuberculosis. While only a minority will progress
to disease, the majority of healthy individuals exposed to M ycobacterium tuberculosis …

Tuberculosis (TB) is still a global health concern, especially in resource-poor countries such
as The Gambia. Defining protective immunity to TB is challenging: its pathogenesis is …

Mycobacterium tuberculosis (MTB) is a leading cause of mortality worldwide from an
infectious agent. Natural killer T (NKT) cells recognize mycobacterial antigens and …

Both innate and adaptive immune systems contribute to host defense against infection with
Mycobacterium tuberculosis. NK cells have been associated with early resistance against …

Tuberculosis is still a leading cause of bacterial infection worldwide, with an estimate of over
two billion people latently infected with Mycobacterium tuberculosis (MTB). A delicate …

Tuberculosis (TB) is a leading global public health problem; however, the mechanisms
underlying the immunopathology of TB progression are not well understood. It is currently …

We characterized the underlying mechanisms by which glutathione (GSH)-enhanced natural
killer (NK) cells inhibit the growth of Mycobacterium tuberculosis (M. tb) inside human …

NK cells were recently suggested to be important for the initial control of M. tuberculosis
infection. The phenotypes of the 3 main NK blood subsets, CD56bright, CD56dim, and …

To gain a better understanding of the pathological role of natural killer (NK) T cells in murine
tuberculosis, NKT knockout (KO) mice (Jα281-/-mice) were utilized. Eight-week-old NKT KO …

Killer immunoglobulin-like receptors (KIR) on natural killer (NK) cells interact with other
immune cells to monitor the immune system and combat infectious diseases, such as …