Liprin-α proteins are adaptors that interact with the receptor protein tyrosine phosphatase
leukocyte common antigen-related (LAR) and other synaptic proteins to promote synaptic …

In the Drosophila visual system, the color-sensing photoreceptors R7 and R8 project their
axons to two distinct layers in the medulla. Loss of the receptor tyrosine phosphatase LAR …

The formation of mammalian synapses entails the precise alignment of presynaptic release
sites with postsynaptic receptors but how nascent cell–cell contacts translate into assembly …

Classical cadherin-mediated interactions between axons and dendrites are critical to target
selection and synapse assembly. However, the molecular mechanisms by which these …

The LAR transmembrane tyrosine phosphatase associates with liprin-α proteins and
colocalizes with liprin-α1 at focal adhesions. LAR has been implicated in axon guidance …

Liprin‐α proteins are major protein constituents of synapses and are important for the
organization of synaptic vesicles and neurotransmitter receptors on their respective sides of …

Synapses are specialized communication junctions between neurons whose plasticity
provides the structural and functional basis for information processing and storage in the …

Here, we examine the synaptic function of the receptor protein tyrosine phosphatase
(RPTP), Dlar, and an associated intracellular protein, Dliprin-α, at the Drosophila larval …

The presynaptic active zone provides sites for vesicle docking and release at central
nervous synapses and is essential for speed and accuracy of synaptic transmission. Liprin-α …

Brain's functions, such as memory and learning, rely on synapses that are highly specialized
cellular junctions connecting neurons. Functional synapses orchestrate the assembly of ion …