Magnetically powered immunogenic macrophage microrobots for targeted multimodal cancer therapy

Y Li, Z Cong, L Xie, S Tang, C Ren, X Peng, D Tang… - Small, 2023 - Wiley Online Library
Motile microrobots open a new realm for disease treatment. However, the concerns of
possible immune elimination, targeted capability and limited therapeutic avenue of …

Remotely guided immunobots engaged in anti‐tumorigenic phenotypes for targeted cancer immunotherapy

NO Dogan, H Ceylan, E Suadiye, D Sheehan, A Aydin… - Small, 2022 - Wiley Online Library
Building medical microrobots from the body's own cells may circumvent the biocompatibility
concern and hence presents more potential in clinical applications to improve the possibility …

Immunomodulation and delivery of macrophages using nano-smooth drug-loaded magnetic microrobots for dual targeting cancer therapy

X Song, W Fu, UK Cheang - Iscience, 2022 - cell.com
To realize the potential to use micro/nanorobots for targeted cancer therapy, it is important to
improve their biocompatibility and targeting ability. Here, we report on drug-loaded magnetic …

Magnetically actuated cell‐robot system: precise control, manipulation, and multimode conversion

Y Dai, L Jia, L Wang, H Sun, Y Ji, C Wang, L Song… - Small, 2022 - Wiley Online Library
Border‐nearing microrobots with self‐propelling and navigating capabilities have promising
applications in micromanipulation and bioengineering, because they can stimulate the …

Precise control of customized macrophage cell robot for targeted therapy of solid tumors with minimal invasion

Y Dai, X Bai, L Jia, H Sun, Y Feng, L Wang, C Zhang… - Small, 2021 - Wiley Online Library
Injecting micro/nanorobots into the body to kill tumors is one of the ultimate ambitions for
medical nanotechnology. However, injecting current micro/nanorobots based on 3D‐printed …

Hybrid-actuating macrophage-based microrobots for active cancer therapy

J Han, J Zhen, V Du Nguyen, G Go, Y Choi, SY Ko… - Scientific reports, 2016 - nature.com
Using macrophage recruitment in tumors, we develop active, transportable, cancer
theragnostic macrophage-based microrobots as vector to deliver therapeutic agents to tumor …

Magnetic torque–driven living microrobots for increased tumor infiltration

T Gwisai, N Mirkhani, MG Christiansen, TT Nguyen… - Science Robotics, 2022 - science.org
Biohybrid bacteria–based microrobots are increasingly recognized as promising externally
controllable vehicles for targeted cancer therapy. Magnetic fields in particular have been …

Macrophage-based microrobots for anticancer therapy: recent progress and future perspectives

VD Nguyen, JO Park, E Choi - Biomimetics, 2023 - mdpi.com
Macrophages, which are part of the mononuclear phagocytic system, possess sensory
receptors that enable them to target cancer cells. In addition, they are able to engulf large …

Magnetically steerable bacterial microrobots moving in 3D biological matrices for stimuli-responsive cargo delivery

MB Akolpoglu, Y Alapan, NO Dogan, SF Baltaci… - Science …, 2022 - science.org
Bacterial biohybrids, composed of self-propelling bacteria carrying micro/nanoscale
materials, can deliver their payload to specific regions under magnetic control, enabling …

An extracellular matrix-mimicking magnetic microrobot for targeted elimination of circulating cancer cells

J Huang, Y Liu, J Wu, F Dong, C Liu, J Luo, X Liu… - Nanoscale, 2024 - pubs.rsc.org
Cancer cells disseminate through the bloodstream, leading to metastasis in distant sites
within the body. One promising strategy to prevent metastasis is to eliminate circulating …