Neutrophil interactions with T cells, platelets, endothelial cells, and of course tumor cells
BH Segal, T Giridharan, S Suzuki… - Immunological …, 2023 - Wiley Online Library
Neutrophils sense microbes and host inflammatory mediators, and traffic to sites of infection
where they direct a broad armamentarium of antimicrobial products against pathogens …
where they direct a broad armamentarium of antimicrobial products against pathogens …
Always look on the bright side: anti-tumor functions of neutrophils
Neutrophils are the most abundant population of white blood cells in the human circulation
playing a critical role in inflammation and in host defense against microbial infections. In …
playing a critical role in inflammation and in host defense against microbial infections. In …
Neutrophils in the tumor microenvironment: trying to heal the wound that cannot heal
KL Singel, BH Segal - Immunological reviews, 2016 - Wiley Online Library
Neutrophils are the first responders to infection and injury and are critical for antimicrobial
host defense. Through the generation of reactive oxidants, activation of granular constituents …
host defense. Through the generation of reactive oxidants, activation of granular constituents …
Neutrophils as active regulators of the immune system in the tumor microenvironment
ME Shaul, ZG Fridlender - Journal of leukocyte biology, 2017 - academic.oup.com
In recent years, the role of immune cells in tumor progression has been a matter of
increasing interest. Neutrophils constitute an important portion of the immune cells infiltrating …
increasing interest. Neutrophils constitute an important portion of the immune cells infiltrating …
[HTML][HTML] Tumor-associated neutrophils in cancer: going pro
The progression of cancer is not only about the tumor cell itself, but also about other
involved players including cancer cell recruited immune cells, their released pro …
involved players including cancer cell recruited immune cells, their released pro …
[HTML][HTML] Heterogeneity of neutrophils in cancer: one size does not fit all
S Chen, Q Zhang, L Lu, C Xu, J Li, J Zha… - Cancer Biology & …, 2022 - ncbi.nlm.nih.gov
Neutrophils play an essential role in the defense against bacterial infections and orchestrate
both the innate and adaptive immune responses. With their abundant numbers, diverse …
both the innate and adaptive immune responses. With their abundant numbers, diverse …
[HTML][HTML] Versatile neutrophil functions in cancer
Neutrophils have historically been considered a singular, terminally-differentiated cell
population, replete with pre-formed granules, poised to react quickly, aggressively, and …
population, replete with pre-formed granules, poised to react quickly, aggressively, and …
Roles of neutrophils in cancer growth and progression
MR Galdiero, G Varricchi, S Loffredo… - Journal of leukocyte …, 2018 - academic.oup.com
Chronic inflammation is a well-known tumor-enabling capacity, which allows nascent tumors
to acquire all the hallmark capabilities, including the escape from immunosurveillance …
to acquire all the hallmark capabilities, including the escape from immunosurveillance …
Neutrophils in the tumor microenvironment
DR Powell, A Huttenlocher - Trends in immunology, 2016 - cell.com
Neutrophils are the first responders to sites of acute tissue damage and infection. Recent
studies suggest that in addition to neutrophil apoptosis, resolution of neutrophil inflammation …
studies suggest that in addition to neutrophil apoptosis, resolution of neutrophil inflammation …
Mechanistic insights into the interplays between neutrophils and other immune cells in cancer development and progression
Cancer is considered a major public health concern worldwide and is characterized by an
uncontrolled division of abnormal cells. The human immune system recognizes cancerous …
uncontrolled division of abnormal cells. The human immune system recognizes cancerous …