Neutrophil interactions with T cells, platelets, endothelial cells, and of course tumor cells

BH Segal, T Giridharan, S Suzuki… - Immunological …, 2023 - Wiley Online Library
Neutrophils sense microbes and host inflammatory mediators, and traffic to sites of infection
where they direct a broad armamentarium of antimicrobial products against pathogens …

Always look on the bright side: anti-tumor functions of neutrophils

S Vols, RV Sionov, Z Granot - Current pharmaceutical design, 2017 - ingentaconnect.com
Neutrophils are the most abundant population of white blood cells in the human circulation
playing a critical role in inflammation and in host defense against microbial infections. In …

Neutrophils in the tumor microenvironment: trying to heal the wound that cannot heal

KL Singel, BH Segal - Immunological reviews, 2016 - Wiley Online Library
Neutrophils are the first responders to infection and injury and are critical for antimicrobial
host defense. Through the generation of reactive oxidants, activation of granular constituents …

Neutrophils as active regulators of the immune system in the tumor microenvironment

ME Shaul, ZG Fridlender - Journal of leukocyte biology, 2017 - academic.oup.com
In recent years, the role of immune cells in tumor progression has been a matter of
increasing interest. Neutrophils constitute an important portion of the immune cells infiltrating …

[HTML][HTML] Tumor-associated neutrophils in cancer: going pro

L Wu, S Saxena, M Awaji, RK Singh - Cancers, 2019 - mdpi.com
The progression of cancer is not only about the tumor cell itself, but also about other
involved players including cancer cell recruited immune cells, their released pro …

[HTML][HTML] Heterogeneity of neutrophils in cancer: one size does not fit all

S Chen, Q Zhang, L Lu, C Xu, J Li, J Zha… - Cancer Biology & …, 2022 - ncbi.nlm.nih.gov
Neutrophils play an essential role in the defense against bacterial infections and orchestrate
both the innate and adaptive immune responses. With their abundant numbers, diverse …

[HTML][HTML] Versatile neutrophil functions in cancer

M Siwicki, MJ Pittet - Seminars in Immunology, 2021 - Elsevier
Neutrophils have historically been considered a singular, terminally-differentiated cell
population, replete with pre-formed granules, poised to react quickly, aggressively, and …

Roles of neutrophils in cancer growth and progression

MR Galdiero, G Varricchi, S Loffredo… - Journal of leukocyte …, 2018 - academic.oup.com
Chronic inflammation is a well-known tumor-enabling capacity, which allows nascent tumors
to acquire all the hallmark capabilities, including the escape from immunosurveillance …

Neutrophils in the tumor microenvironment

DR Powell, A Huttenlocher - Trends in immunology, 2016 - cell.com
Neutrophils are the first responders to sites of acute tissue damage and infection. Recent
studies suggest that in addition to neutrophil apoptosis, resolution of neutrophil inflammation …

Mechanistic insights into the interplays between neutrophils and other immune cells in cancer development and progression

Z Mahmud, A Rahman, ID Mishu, Y Kabir - Cancer and Metastasis …, 2022 - Springer
Cancer is considered a major public health concern worldwide and is characterized by an
uncontrolled division of abnormal cells. The human immune system recognizes cancerous …