Mycophenolate mofetil as first-line treatment improves clinically evident early scleroderma lung disease

SNC Liossis, A Bounas, AP Andonopoulos - Rheumatology, 2006 - academic.oup.com
Objective. To find an effective, safe immunosuppressive regimen as an alternative to
cyclophosphamide (Cy) for the treatment of clinically evident diffuse scleroderma (dSSc) …

Effect of mycophenolate mofetil on pulmonary function in scleroderma-associated interstitial lung disease

AJ Gerbino, CH Goss, JA Molitor - Chest, 2008 - Elsevier
Objective We sought to determine the effectiveness of mycophenolate mofetil (MMF) in
scleroderma-associated interstitial lung disease (SSc-ILD). Methods We retrospectively …

Mycophenolate mofetil versus placebo for systemic sclerosis–related interstitial lung disease: an analysis of scleroderma lung studies I and II

ER Volkmann, DP Tashkin, N Li, MD Roth… - Arthritis & …, 2017 - Wiley Online Library
Objective To compare mycophenolate mofetil (MMF) with placebo for the treatment of
systemic sclerosis (SSc)–related interstitial lung disease (ILD). Methods We included …

Effect of mycophenolate sodium in scleroderma-related interstitial lung disease

CP Simeón-Aznar, V Fonollosa-Plá… - Clinical …, 2011 - Springer
This study aims to determine the effectiveness of mycophenolate sodium (MS) in patients
with scleroderma (SSc)-related interstitial lung disease (ILD). In a prospective observational …

Cyclophosphamide versus mycophenolate mofetil in scleroderma interstitial lung disease (SSc-ILD) as induction therapy: a single-centre, retrospective analysis

PD Shenoy, M Bavaliya, S Sashidharan… - Arthritis research & …, 2016 - Springer
Background Scleroderma is a systemic autoimmune disease characterized mainly by skin
manifestations and involvement of various visceral organs, especially the lungs. Lung …

[HTML][HTML] Use of mycophenolate mofetil to treat scleroderma-associated interstitial lung disease

AC Zamora, PJ Wolters, HR Collard, MK Connolly… - Respiratory …, 2008 - Elsevier
Up to 80% of patients with scleroderma have lung disease, with interstitial lung disease
(ILD) being the most common manifestation. Currently, there is no definitive therapy for this …

[PDF][PDF] Mycophenolate mofetil is an effective and safe option for the management of systemic sclerosis-associated interstitial lung disease: results from the Australian …

C Owen, GS Ngian, K Elford, O Moore… - Clin Exp …, 2016 - clinexprheumatol.org
Objective. To report the efficacy and tolerability of mycophenolate mofetil (MMF) and
azathioprine (AZA) in the management of systemic sclerosis-associated interstitial lung …

Oral cyclophosphamide improves pulmonary function in scleroderma patients with fibrosing alveolitis: experience in one centre

L Beretta, M Caronni, M Raimondi, A Ponti… - Clinical …, 2007 - Springer
Lung involvement constitutes nowadays the major cause of morbidity and mortality in
scleroderma patients. Pulmonary fibrosis in systemic sclerosis (SSc) is thought to be the …

Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group …

DP Tashkin, MD Roth, PJ Clements… - The lancet Respiratory …, 2016 - thelancet.com
Background 12 months of oral cyclophosphamide has been shown to alter the progression
of scleroderma-related interstitial lung disease when compared with placebo. However …

Effect of mycophenolate mofetil (MMF) on systemic sclerosis-related interstitial lung disease with mildly impaired lung function: a double-blind, placebo-controlled …

G Naidu, SK Sharma, MB Adarsh, V Dhir… - Rheumatology …, 2020 - Springer
The efficacy and safety of mycophenolate mofetil (MMF) has been studied in patients with
systemic sclerosis (SSc)-related interstitial lung disease (ILD) with moderate–severe …