PM2. 5 induces ferroptosis in human endothelial cells through iron overload and redox imbalance
Y Wang, M Tang - Environmental pollution, 2019 - Elsevier
PM2. 5 is becoming a worldwide environmental problem, which profoundly endangers
public health, thus progressively capturing public attention this decade. As a fragile target of …
public health, thus progressively capturing public attention this decade. As a fragile target of …
Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell
T Bai, M Li, Y Liu, Z Qiao, Z Wang - Free Radical Biology and Medicine, 2020 - Elsevier
Atherosclerosis (AS) is the fundamental pathological state of many serious vascular
diseases, characterized by disorders of lipid metabolism. Ferroptosis is a type of regulated …
diseases, characterized by disorders of lipid metabolism. Ferroptosis is a type of regulated …
Ferroptosis is involved in the benzene-induced hematotoxicity in mice via iron metabolism, oxidative stress and NRF2 signaling pathway
R Sun, M Liu, K Xu, Y Pu, J Huang, J Liu… - Chemico-biological …, 2022 - Elsevier
Benzene is a pollutant that widely exists in the environment and in occupational workplaces.
Its exposure is closely associated with hematological disorders and even leukemia, which …
Its exposure is closely associated with hematological disorders and even leukemia, which …
[HTML][HTML] Ferroptosis: a potential target in cardiovascular disease
Y Leng, X Luo, J Yu, H Jia, B Yu - Frontiers in Cell and …, 2022 - frontiersin.org
Ferroptosis is a new form of regulatory cell death characterized by iron-dependent and
intracellular lipid peroxidation. Ferroptosis can be divided into two stages. The first stage is …
intracellular lipid peroxidation. Ferroptosis can be divided into two stages. The first stage is …
[HTML][HTML] The role of macrophage iron overload and ferroptosis in atherosclerosis
J Ma, H Zhang, Y Chen, X Liu, J Tian, W Shen - Biomolecules, 2022 - mdpi.com
Ferroptosis is a new type of cell death caused by iron-dependent lipid peroxidation. In recent
years, it has been found that ferroptosis can promote the progression of atherosclerosis …
years, it has been found that ferroptosis can promote the progression of atherosclerosis …
[HTML][HTML] Endothelial cell ferroptosis mediates monocrotaline-induced pulmonary hypertension in rats by modulating NLRP3 inflammasome activation
SS Xie, Y Deng, S Guo, J Li, Y Zhou, J Liao, D Wu… - Scientific reports, 2022 - nature.com
Inflammation triggers pulmonary vascular remodelling. Ferroptosis, a nonapoptotic form of
cell death that is triggered by iron-dependent lipid peroxidation and contributes to the …
cell death that is triggered by iron-dependent lipid peroxidation and contributes to the …
SIRT1-autophagy axis inhibits excess iron-induced ferroptosis of foam cells and subsequently increases IL-1Β and IL-18
G Su, W Yang, S Wang, C Geng, X Guan - Biochemical and Biophysical …, 2021 - Elsevier
Objective Ferroptosis is a new form of programmed cell death characterized by an iron-
dependent increase in lipid ROS. It has recently been reported that elevated iron levels in …
dependent increase in lipid ROS. It has recently been reported that elevated iron levels in …
[HTML][HTML] Interplay of Nrf2 and BACH1 in inducing ferroportin expression and enhancing resistance of human macrophages towards ferroptosis
D Namgaladze, DC Fuhrmann, B Brüne - Cell Death Discovery, 2022 - nature.com
Compared to cancer cells, macrophages are inert to lipid peroxidation-triggered, iron-
dependent cell death known as ferroptosis. Mechanisms underlying macrophage resistance …
dependent cell death known as ferroptosis. Mechanisms underlying macrophage resistance …
Ferroptosis and cardiovascular disease: role of free radical-induced lipid peroxidation
X Chen, X Li, X Xu, L Li, N Liang, L Zhang… - Free radical …, 2021 - Taylor & Francis
Cardiovascular disease (CVD), including heart attack, stroke, heart failure, arrhythmia, and
other congenital heart diseases remain the leading cause of morbidity and mortality …
other congenital heart diseases remain the leading cause of morbidity and mortality …
[HTML][HTML] Mechanisms of ferroptosis and relations with regulated cell death: a review
P Lei, T Bai, Y Sun - Frontiers in physiology, 2019 - frontiersin.org
Ferroptosis is a newly identified form of nonapoptotic regulated cell death (RCD)
characterized by iron-dependent accumulation of lipid peroxides. It is morphologically and …
characterized by iron-dependent accumulation of lipid peroxides. It is morphologically and …