Polycystic liver disease: advances in understanding and treatment
TV Masyuk, AI Masyuk… - Annual Review of …, 2022 - annualreviews.org
Polycystic liver disease (PLD) is a group of genetic disorders characterized by progressive
development of cholangiocyte-derived fluid-filled hepatic cysts. PLD is the most common …
development of cholangiocyte-derived fluid-filled hepatic cysts. PLD is the most common …
An update on the pathophysiology and management of polycystic liver disease
MYW Wong, GW McCaughan… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Polycystic liver disease (PLD) is characterized by the presence of multiple
cholangiocyte-derived hepatic cysts that progressively replace liver tissue. They are …
cholangiocyte-derived hepatic cysts that progressively replace liver tissue. They are …
Therapeutic targets in polycystic liver disease
T V. Masyuk, A I. Masyuk, N F. LaRusso - Current drug targets, 2017 - benthamdirect.com
Polycystic liver diseases (PLD) are a group of genetic disorders initiated by mutations in
several PLD-related genes and characterized by the presence of multiple cholangiocyte …
several PLD-related genes and characterized by the presence of multiple cholangiocyte …
Polycystic liver diseases: advanced insights into the molecular mechanisms
MJ Perugorria, TV Masyuk, JJ Marin… - Nature reviews …, 2014 - nature.com
Polycystic liver diseases are genetic disorders characterized by progressive bile duct
dilatation and/or cyst development. The large volume of hepatic cysts causes different …
dilatation and/or cyst development. The large volume of hepatic cysts causes different …
Polycystic liver disease: the benefits of targeting cAMP
NF Larusso, TV Masyuk, MC Hogan - Clinical Gastroenterology and …, 2016 - cghjournal.org
(ADPLD) or in association with autosomal-dominant polycystic kidney disease (ADPKD) or
autosomal-recessive polycystic kidney disease (ARPKD). PLD is characterized by the …
autosomal-recessive polycystic kidney disease (ARPKD). PLD is characterized by the …
Polycystic liver diseases: congenital disorders of cholangiocyte signaling
M Strazzabosco, S Somlo - Gastroenterology, 2011 - Elsevier
Polycystic liver diseases (PLD) are inherited disorders of the biliary epithelium, caused by
genetic defects in proteins associated with intracellular organelles, mainly the endoplasmic …
genetic defects in proteins associated with intracellular organelles, mainly the endoplasmic …
Genetics, pathobiology and therapeutic opportunities of polycystic liver disease
P Olaizola, PM Rodrigues… - Nature Reviews …, 2022 - nature.com
Polycystic liver diseases (PLDs) are inherited genetic disorders characterized by
progressive development of intrahepatic, fluid-filled biliary cysts (more than ten), which …
progressive development of intrahepatic, fluid-filled biliary cysts (more than ten), which …
New advances in polycystic liver diseases
A Santos-Laso, L Izquierdo-Sánchez… - Seminars in Liver …, 2017 - thieme-connect.com
Polycystic liver diseases (PLDs) include a heterogeneous group of congenital disorders
inherited as dominant or recessive genetic traits; they are manifested alone or in association …
inherited as dominant or recessive genetic traits; they are manifested alone or in association …
Polycystic liver diseases
Polycystic liver diseases (PCLDs) are genetic disorders with heterogeneous etiologies and
a range of phenotypic presentations. PCLD exhibits both autosomal or recessive dominant …
a range of phenotypic presentations. PCLD exhibits both autosomal or recessive dominant …
Advances in management of polycystic liver disease
GT Everson, SM Helmke, B Doctor - Expert Review of …, 2008 - Taylor & Francis
The focus of this review is polycystic liver disease, a genetic disorder characterized by
multiple macroscopic liver cysts that initially bud from biliary epithelium but subsequently …
multiple macroscopic liver cysts that initially bud from biliary epithelium but subsequently …
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