Fragile X syndrome (FXS) is the most common inherited form of intellectual disability in
humans. In addition to cognitive impairment, patients may exhibit hyperactivity, attention …

Fragile X syndrome (FXS) results from the loss of expression of the fragile X mental
retardation (FMR1) gene. Individuals affected by FXS experience many behavioral …

Fragile X syndrome (FXS) is a developmental disorder caused by a mutation in the X‐linked
FMR1 gene, coding for the FMRP protein which is largely involved in synaptic function. FXS …

Fragile X syndrome (FXS) is a monogenic disease caused by mutations in the FMR1 gene.
The Fmr1 knockout (KO) mice show many aspects of FXS-related phenotypes, and have …

The loss of fragile X mental retardation (FMR1) gene function causes fragile X syndrome
(FXS), a common mental retardation syndrome. Anxiety and abnormal social behaviors are …

Fragile X Syndrome is the most common form of inherited mental retardation. It is also
known for having a substantial behavioral morbidity, including autistic features. In humans …

Summary Fragile X Syndrome (FXS) is a commonly inherited form of intellectual disability
and one of the leading genetic causes for autism spectrum disorder. Clinical symptoms of …

Objective In this study, we used a systemic Fmr1 knockout in order to investigate both
genotype‐and sex‐specific differences across multiple measures of sociability, repetitive …

Autism is a pervasive developmental disorder appearing before the age of 3, where
communication and social interactions are impaired. It also entails stereotypic behavior or …

Background No animal models of autism spectrum disorders (ASD) with good construct
validity are currently available; using genetic models of pathologies characterized by ASD …