Interplay between exosomes, microRNAs and toll-like receptors in brain disorders

V Paschon, SH Takada, JM Ikebara, E Sousa… - Molecular …, 2016 - Springer
Extracellular vesicles (EVs), including exosomes, microvesicles and apoptotic bodies,
participate in intercellular communication, and particularly, in paracrine and endocrine …

The pathogenic, therapeutic and diagnostic role of exosomal microRNA in the autoimmune diseases

R Mirzaei, F Zamani, M Hajibaba… - Journal of …, 2021 - Elsevier
Exosomes are a nano-vesicle surrounded by a bilipid layer that can release from almost all
cells and could be detected in tissues and biological liquids. These vesicles contain lipids …

Vesicular transport of encapsulated microRNA between glial and neuronal cells

WJ Lukiw, AI Pogue - International journal of molecular sciences, 2020 - mdpi.com
Exosomes (EXs) and extracellular microvesicles (EMVs) represent a diverse assortment of
plasma membrane-derived nanovesicles, 30–1000 nm in diameter, released by all cell …

No small matter: Emerging roles for exosomal miRNAs in the immune system

KM Bauer, JL Round, RM O'Connell - The FEBS Journal, 2022 - Wiley Online Library
Extracellular communication is critical to the function of an organism. Exosomes, small lipid
extracellular vesicles, have been recently appreciated to participate in this vital function …

Exosomal miRNA-mediated intercellular communications and immunomodulatory effects in tumor microenvironments

HM Nail, CC Chiu, CH Leung, MMM Ahmed… - Journal of biomedical …, 2023 - Springer
Extracellular communication, in other words, crosstalk between cells, has a pivotal role in
the survival of an organism. This communication occurs by different methods, one of which is …

Emerging potential of exosomes and noncoding microRNAs for the treatment of neurological injury/diseases

M Chopp, ZG Zhang - Expert opinion on emerging drugs, 2015 - Taylor & Francis
Recent discoveries of cellular generation of exosomes, small (∼ 30–100 nm) complex lipid
membrane structures which encapsulate and transport proteins, RNAs, including …

Extracellular vesicles mediate intercellular communication: Transfer of functionally active microRNAs by microvesicles into phagocytes

L Claßen, LO Tykocinski, F Wiedmann… - European Journal of …, 2017 - Wiley Online Library
Cell activation and apoptosis lead to the formation of extracellular vesicles (EVs) such as
exosomes or microvesicles (MVs). EVs have been shown to modulate immune responses; …

Modulation of cellular function through immune-activated exosomes

L Pulliam, A Gupta - DNA and cell biology, 2015 - liebertpub.com
Extracellular vesicles classified as exosomes, microvesicles, or apoptotic bodies based on
size are shed from most cells under normal as well as pathological conditions. They are …

Neuroinflammation and depression: microglia activation, extracellular microvesicles and microRNA dysregulation

D Brites, A Fernandes - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Patients with chronic inflammation are often associated with the emergence of depression
symptoms, while diagnosed depressed patients show increased levels of circulating …

The role of exosomal microRNAs in central nervous system diseases

Y Yu, K Hou, T Ji, X Wang, Y Liu, Y Zheng, J Xu… - Molecular and cellular …, 2021 - Springer
Abstract MicroRNAs (miRNA), endogenous non-coding RNAs approximately 22 nucleotides
long, regulate gene expression by mediating translational inhibition or mRNA degradation …