Mechanisms of resistance to chemotherapy in gastric cancer

JJG Marin, R Al-Abdulla, E Lozano… - Anti-Cancer Agents …, 2016 - ingentaconnect.com
Although surgical resection is the standard curative therapy for gastric cancer, these tumors
are often diagnosed at an advanced stage, when surgery is not recommended. Alternative …

[HTML][HTML] Molecular mechanisms of chemoresistance in gastric cancer

WJ Shi, JB Gao - World journal of gastrointestinal oncology, 2016 - ncbi.nlm.nih.gov
Gastric cancer is the fourth most common cancer and the second leading cause of cancer
deaths worldwide. Chemotherapy is one of the major treatments for gastric cancer, but drug …

Current advances and outlook in gastric cancer chemoresistance: a review

SX Zhang, W Liu, B Ai, LL Sun… - Recent patents on anti …, 2022 - ingentaconnect.com
Background: Surgical resection of the lesion is the standard primary treatment of gastric
cancer. Unfortunately, most patients are already in the advanced stage of the disease when …

A review of research progress in multidrug-resistance mechanisms in gastric cancer

T Ruan, W Liu, K Tao, C Wu - OncoTargets and therapy, 2020 - Taylor & Francis
Gastric cancer is one of the most common malignant tumors, and it is also one of the leading
causes of cancer death worldwide. Because of its insidious symptoms and lack of early …

Molecular bases of mechanisms accounting for drug resistance in gastric adenocarcinoma

JJG Marin, L Perez-Silva, RIR Macias, M Asensio… - Cancers, 2020 - mdpi.com
Gastric adenocarcinoma (GAC) is the most common histological type of gastric cancer, the
fifth according to the frequency and the third among the deadliest cancers. GAC high …

Resistance mechanisms of gastrointestinal cancers: why does conventional chemotherapy fail?

F Gieseler, P Rudolph, G Kloeppel… - International journal of …, 2003 - Springer
Background Gastrointestinal cancers belong to the most important causes of cancer death in
the Western world. Because cure can be achieved only by complete surgical removal of the …

New insights into the mechanisms of gastric cancer multidrug resistance and future perspectives

D Zhang, D Fan - Future Oncology, 2010 - Taylor & Francis
Gastric cancer is still the second leading cause of cancer death worldwide. Chemotherapy is
one of the major treatment options for advanced gastric cancer. The efficacy of …

Progress and current status of molecule-targeted therapy and drug resistance in gastric cancer.

Z Chen, Y Li, B Tan, Q Zhao, L Fan, F Li… - Drugs of today …, 2020 - europepmc.org
Gastric cancer is one of the most common malignant tumors in the world. In China, its
morbidity and mortality are second only to lung cancer. Chemotherapy combined with …

Molecular mechanism of resistance to chemotherapy in gastric cancers, the role of autophagy

LV Spirina, AV Avgustinovich, SG Afanas' ev… - Current drug …, 2020 - ingentaconnect.com
Gastric cancer (GC) is biologically and genetically heterogeneous with complex
carcinogenesis at the molecular level. Despite the application of multiple approaches in the …

Establishment and characterization of multidrug-resistant gastric cancer cell lines

X Zhang, M Yashiro, H Qiu, T Nishii… - Anticancer …, 2010 - ar.iiarjournals.org
Aim: The aim of this study was to establish drug-resistant cell lines and to elucidate
mechanisms leading to multi-drug resistance in gastric cancer. Materials and Methods: Five …