Considerable evidence now indicates that a separate and distinct renin-angiotensin system
(RAS) is present within the brain. The necessary precursors and enzymes required for the …

The existence of a brain renin-angiotensin system (RAS) as one of various tissue RASs is
now firmly established. Angiotensin-containing pathways within brain areas involved in …

The discovery that all components of the reninangiotensin system (RAS) are present in the
brain led investigators to postulate the existence of a local brain RAS. Supporting this …

Hypertension affects 26% of adults and is in constant progress related to increased
incidence of obesity and diabetes. One-third of hypertensive patients may be successfully …

In this review, the emerging functional roles of the brain angiotensin system have been
considered. The major effects of Ang II can be classified into three groups, which imply three …

Considerable evidence now suggests that the precursors and enzymes necessary for the
formation and degradation of biologically active forms of angiotensins are present in brain …

The brain renin–angiotensin system continues to be enigmatic more than 40 years after the
brain was first recognized to be a site of action of angiotensin II. This review focuses on the …

The actions of the renin-angiotensin system (RAS) are mediated by the octapeptide
angiotensin II and smaller fragments of it [l-3]. These angiotensins all originate from …

The renin-angiotensin system (RAS) is one of the best-studied enzyme-neuropeptide
systems in the brain and can serve as a model for the action of peptides on neuronal …

The renin-angiotensin system in the brain acts to regulate a number of physiological
processes. Evidence suggests that angiotensin peptides may act as neurotransmitters …