This review covers basic aspects of histone modification and the role of posttranslational
histone modifications in the development of allergic diseases, including the immune …

Chronic inflammatory diseases, including allergies and asthma, are the result of complex
gene-environment interactions. One of the most challenging questions in this regard relates …

Objective To review current research findings in the field of epigenetics pertaining to the
developmental origins of allergic disease. Data Sources We examined original research and …

Asthma is heritable, influenced by the environment, and modified by in utero exposures and
aging; all of these features are also common to epigenetic regulation. Furthermore, the …

The role of epigenetics in allergy and asthma development : Current Opinion in Allergy and
Clinical Immunology The role of epigenetics in allergy and asthma development : Current …

Diverse cellular functions including the regulation of inflammatory gene expression, DNA
repair and cell proliferation are regulated by epigenetic changes. Transcriptional co …

Several studies show that childhood and adulthood asthma and its symptoms can be
modulated through epigenetic modifications. Epigenetic changes are inheritable …

Epigenetics of asthma and allergic disease is a field that has expanded greatly in the last
decade. Previously thought only in terms of cell differentiation, it is now evident the …

The multiple inter-dependent post-translational modifications of histones represent fine
regulators of chromatin dynamics. These covalent modifications, including phosphorylation …

Epigenetic mechanisms mediate genomic adaption to the environment and epigenetic
alterations can contribute to the development of disease phenotypes, as can genetic …