Antiphospholipid antibodies and the antiphospholipid syndrome: pathogenic mechanisms

SS Pierangeli, PP Chen, E Raschi… - … in thrombosis and …, 2008 - thieme-connect.com
Antiphospholipid antibodies (Abs) are associated with thrombosis and are a risk factor for
recurrent pregnancy loss and obstetric complications in patients with the antiphospholipid …

The antiphospholipid syndrome

JH Rand - Annual review of medicine, 2003 - annualreviews.org
The antiphospholipid (aPL) antibody syndrome is an autoimmune condition in which
vascular thrombosis and/or recurrent pregnancy losses occur in patients with laboratory …

Pathogenesis and management of antiphospholipid syndrome

DRJ Arachchillage, M Laffan - British journal of haematology, 2017 - Wiley Online Library
Antiphospholipid antibodies are a heterogeneous group of autoantibodies that have clear
associations with thrombosis and pregnancy morbidity, and which together constitute the …

Antiphospholipid syndrome: an overview

JG Hanly - Cmaj, 2003 - Can Med Assoc
ANTIPHOSPHOLIPID ANTIBODIES ARE A HETEROGENEOUS GROUP of autoantibodies
that are detected by immunoassays and functional coagulation tests. The antigenic targets …

The antiphospholipid syndrome: from pathophysiology to treatment

S Negrini, F Pappalardo, G Murdaca, F Indiveri… - Clinical and …, 2017 - Springer
Antiphospholipid antibody syndrome (APS) is an autoimmune acquired thrombophilia
characterized by recurrent thrombosis and pregnancy morbidity in the presence of …

[HTML][HTML] Pathophysiology of the antiphospholipid syndrome

PG De Groot, R Derksen - Journal of Thrombosis and Haemostasis, 2005 - Elsevier
Antiphospholipid syndrome is a distinct disorder with the clinical features of recurrent
thrombosis in the venous or arterial circulation and fetal losses. Its serological marker is the …

Pathophysiology of thrombosis and pregnancy morbidity in the antiphospholipid syndrome

K Oku, O Amengual, T Atsumi - European journal of clinical …, 2012 - Wiley Online Library
Eur J Clin Invest 2012; 42 (10): 1126–1135 Abstract In patients with the antiphospholipid
syndrome (APS), the presence of a group of pathogenic autoantibodies called …

Pathogenic mechanisms mediating antiphospholipid syndrome

PL Meroni, P Riboldi - Current opinion in rheumatology, 2001 - journals.lww.com
Antiphospholipid antibodies are the marker for antiphospholipid syndrome. There is
evidence that these autoantibodies lead to both thrombotic diathesis and obstetrical …

The pathogenesis of the antiphospholipid syndrome

B Giannakopoulos, SA Krilis - New England Journal of Medicine, 2013 - Mass Medical Soc
The antiphospholipid syndrome is a prothrombotic disorder associated with autoantibodies.
It is associated with obstetrical complications (mainly spontaneous abortion) as well as …

Antiphospholipid antibody syndrome

WH Kutteh, CD Hinote - Obstetrics and Gynecology Clinics, 2014 - obgyn.theclinics.com
Antiphospholipid antibodies (aPLs) are acquired antibodies (immunoglobulin [Ig] G, IgM,
and/or IgA isotypes) that react against negatively charged phospholipids. They were …