Design of activatable NIR-II molecular probe for in vivo elucidation of disease-related viscosity variations

K Dou, W Huang, Y Xiang, S Li, Z Liu - Analytical chemistry, 2020 - ACS Publications
A clear elucidation of a disease-related viscosity change in vivo is significant yet highly
challenging as well. Fluorescence imaging in the second near-infrared region (NIR-II, 1000 …

A mitochondria-targeted near-infrared fluorescent probe for imaging viscosity in living cells and a diabetic mice model

B Chen, S Mao, Y Sun, L Sun, N Ding, C Li… - Chemical …, 2021 - pubs.rsc.org
A mitochondria-targeted near-infrared fluorescent probe NIR-V with 700 nm emission was
designed to monitor cell viscosity changes with high selectivity and sensitivity, which was …

A mitochondrial-targeting near-infrared fluorescent probe for visualizing and monitoring viscosity in live cells and tissues

Y Zhang, Z Li, W Hu, Z Liu - Analytical chemistry, 2019 - ACS Publications
The intracellular viscosity is closely related to many functional disorders and diseases.
Especially, abnormal mitochondrial viscosity changes are one of the distinct indications in …

Constructing a NIR fluorescent probe for ratiometric imaging viscosity in mice and detecting blood viscosity in folliculitis mice and peritonitis mice

L Zhu, W Lin - Sensors and Actuators B: Chemical, 2022 - Elsevier
For a variety of viscosity-related diseases, studying blood viscosity may be an ever so direct,
simple, non-invasive as well as effective pre-diagnostic method. At present, the main cause …

Mitochondrial-targeting near-infrared fluorescent probe for visualizing viscosity in drug-induced cells and a fatty liver mouse model

Y Wu, C Yin, W Zhang, Y Zhang, F Huo - Analytical Chemistry, 2022 - ACS Publications
Mitochondria, as “cell energy stations”, are involved in the regulation of various cell
functions. Recent investigations revealed that mitochondrial dysfunction that can cause an …

Synergistic effects of multiple rotors and hydrogen-bond interactions lead to sensitive near-infrared viscosity probes for live-cell microscopy

D Li, T Shen, X Xue, W Chen, W Tao, W Chi… - Science China …, 2023 - Springer
Abstract Changes in cellular viscosity are associated with various physiological processes
and pathological conditions. To study these cellular processes and functions, highly …

Viscosity-responsive NIR-II fluorescent probe with aggregation-induced emission features for early diagnosis of liver injury

J Ge, W Cai, N Niu, Y Wen, Q Wu, L Wang, D Wang… - Biomaterials, 2023 - Elsevier
As the primary organ for drug metabolism and detoxification, the liver is susceptible to
damage and seriously impaired function. In situ diagnosing and real-time monitoring of liver …

A near-infrared aggregation-induced emission probe for imaging lipid droplet and in vivo visualization of diabetes-related viscosity variations

H Wang, H Zheng, W Zhang, L Yang, M Yu… - Sensors and Actuators B …, 2023 - Elsevier
As a pivotal parameter of microenvironment, viscosity is closely related to many diseases
and dysfunction in vivo. Lipid droplets, as organelles that store and metabolize lipids, are …

Small molecular fluorescent probes for imaging of viscosity in living biosystems

H Xiao, P Li, B Tang - Chemistry–A European Journal, 2021 - Wiley Online Library
Viscosity, as a vital microenvironment parameter, is tightly associated with multitudinous
cellular processes and diseases. Recently, precise visualization of viscosity has started to …

A sensitive NIR mitochondria-targeting fluorescence probe for visualizing viscosity in living cells and mice

Q Chen, XF Zhang, T Wang, XQ Cao, SL Shen - Analytica Chimica Acta, 2022 - Elsevier
Mitochondria are the powerhouses in cells, providing the energy needed for cellular
activities. However, the abnormalities in the mitochondrial microenvironment (eg, the …